瓜蒌皮注射液住院医嘱专项点评结果与分析

Results and analysis of special comments on inpatient medical orders of Gualoupi injection

目的对我院瓜蒌皮注射液医嘱进行专项点评,为其临床规范使用提供参考依据。方法利用本院的医院信息管理系统(HIS)提取出院时间为2020年10月1日至2021年9月30日所有使用瓜蒌皮注射液的住院患者用药信息和医嘱,共计5615份(含497例患者)。依据《处方管理办法》、药品说明书及文献,分析瓜蒌皮注射液溶媒、用法用量、适应证、疗程及联合用药情况。结果我院使用瓜蒌皮注射液的过程中,溶媒不适宜医嘱136份,用法用量不适宜医嘱81份,超适应证使用医嘱35份;在瓜蒌皮注射液使用过程中,存在超出或不足用药疗程的情况;联合用药中排名前三的药物有硫酸氢氯吡格雷片、阿司匹林肠溶片、阿托伐他汀钙片。结论我院在使用瓜蒌皮注射液时存在一些不规范情况,临床使用过程中应关注其安全性,规范合理用药。

Objective To make a special comment on the medical orders of Gualoupi injection in our hospital,and to provide reference for its clinical standardized use.Methods The hospital information system(HIS)of our hospital was used to extract the medication information and medical orders of all inpatients using Gualoupi injection from October 1,2020 to September 30,2021,a total of 5615 copies(including 497 patients).According to the"prescription management measures",drug instructions and literature,the solvent,usage and dosage,indications,course of treatment and combined medication of Gualoupi injection were analyzed.Results In the process of using Gualoupi injection in our hospital,136 medical orders were not suitable for solvent,81 medical orders were not suitable for usage and dosage,and 35 medical orders were used beyond indications;in the process of using Gualoupi injection,there was a situation of exceeding or insufficient course of treatment;the top three drugs in the combination were clopidogrel hydrogen sulfate tablets,aspirin enteric-coated tablets and atorvastatin calcium tablets.Conclusion There are some irregularities in the use of Gualoupi injection in our hospital.In the clinical use process,we should pay attentions to its safety and standardize the rational use of drugs.