中国农村老年人群抑郁症患病率的Meta分析

Prevalence of depression among elderly populations in rural China:a meta-analysis

目的 系统评价2010年至2023年中国农村60岁及以上老年人群抑郁症的患病率。方法 计算机检索CNKI、WanFang Data、VIP、CBM、PubMed、Embase和Cochrane Library数据库,搜集有关中国60岁及以上农村老年人群抑郁症患病率的横断面研究,检索时限均为2010年1月至2023年3月。由2名研究者独立筛选文献、提取资料并评价纳入研究的偏倚风险后,采用Stata 17.0软件进行Meta分析。结果 共纳入23个横断面研究,总样本量34 916人,抑郁症患病11 308人。Meta分析结果显示,中国农村老年人抑郁症患病率为31.02%[95%CI(26.10%,36.16%)]。亚组分析结果显示,女性老年人群患病率高于男性;GDS-30量表检出率最高,其次是CES-D-10和GDS-15量表;中西部地区患病率高于东部地区;2015年后进行的调查患病率高于2015年前的调查。此外,70岁及以上人群、非已婚、文盲或半文盲、自评健康状况较差、独居、经济状况差、患有慢性病、社会活动少的农村老年人群的抑郁症患病率较高。结论 中国农村老年人群抑郁症患病率较高,但不同特征的老年人群中抑郁症的患病率存在显著差异,在改善农村老年人的心理健康方面应更加重视对高危人群的干预。受纳入研究数量和质量限制,上述结论尚需开展更多高质量研究予以验证。

Objective To systematically review the prevalence of depression in rural Chinese population aged 60 and above from 2010 to 2023.Methods The CNKI、WanFang Data、VIP、CBM、PubMed、Embase and Cochrane Library databases were electronically searched to collect cross-sectional studies on the prevalence of depression of elderly populations in rural China from January 2010 to March 2023.Two reviewers independently screened literature,extracted data,and assessed the risk of bias of the included studies.Meta-analysis was then performed using Stata 17.0 software.Results A total of 23 cross-sectional studies with a total sample of 34916 cases and 11308 depression patients were included.The meta-analysis results showed that the prevalence of depression in rural Chinese population was 31.02%(95%CI 26.10%to 36.16%).Subgroup analysis showed that the prevalence was higher among females than males;the GDS-30 scale had the highest detection rate,followed by the CES-D-10 and GDS-15 scales;the prevalence was higher in the Midwest than in the East;and the prevalence was higher in surveys conducted after 2015 than in 2015 and before.In addition,the prevalence of depression was higher in the rural elderly population aged 70 and above,non-married,illiterate or semi-literate,with poor self-rated health status,living alone,in poor economic status,with chronic diseases,and with low social activity.Conclusion The prevalence of depression is high among the rural elderly population in China,and there are significant disparities in the prevalence of different characteristics of the elderly.These differences should be given more attention to improve the mental health of the rural elderly population.Due to the limited quantity and quality of the included studies,more high-quality studies are needed to verify the above conclusion.