生辰的五运六气属性与2型糖尿病发病的相关性研究

Study on the Correlation Between the Attributes of Five Circuits and Six Qi of Birth Date and the Incidence of Type 2 Diabetes Mellitus

【目的】总结生辰的五运六气属性与2型糖尿病发病风险的相关性,探究五运六气对2型糖尿病的作用及原理,为临床应用五运六气理论防治2型糖尿病提供客观依据。【方法】采用单因素病例对照研究,纳入2020年10月~2022年1月在广州中医药大学第一附属医院、广东省中西医结合医院、广东省第二中医院、佛山市中医院等4所三甲医院的门诊或住院部接受治疗的患者,共3332例。其中,2型糖尿病组2012例,非2型糖尿病组1320例。收集2组患者的年龄、性别、生辰等资料,通过运气学推算方法,得出每位患者的岁运、主运、客运、司天与在泉之气、主气、客气、运气同化、客主加临属性,运用非参数检验、卡方检验等统计学方法对数据进行处理分析,探讨生辰的五运六气属性与2型糖尿病发病风险的关系。【结果】(1)2型糖尿病组与非2型糖尿病组患者的年龄、性别分布比较,差异均无统计学意义(P>0.05)。(2)在岁运分布上,2型糖尿病组中太金所占百分比(14.17%)高于非2型糖尿病组(11.14%),差异有统计学意义(P<0.05),其余岁运属性分布两组间比较,差异均无统计学意义(P>0.05)。(3)在司天之气与在泉之气这一搭配的分布上,2型糖尿病组太阳-太阴所占百分比(19.53%)明显高于非2型糖尿病组(16.21%),差异有统计学意义(P<0.05),其余5种司天-在泉分布两组间比较,差异均无统计学意义(P>0.05)。(4)在主运、客运、主气、客气、运气同化、客主加临的属性分布方面,两组间比较,差异均无统计学意义(P>0.05)。【结论】可能增加2型糖尿病发病风险的生辰五运六气属性为:岁运太金、太阳寒水司天、太阴湿土在泉。另外,主运太火、客气阳明燥金、客主加临为“主气克客气”均可能使罹患2型糖尿病的风险增加,但目前尚不肯定。客运、主气、运气同化方面,均未发现可增加2型糖尿病发病风险的属性。本研究未发现可降低2型糖尿病发病风险的生辰五运六气属性。

Objective To investigate the correlation between the attributes of the five circuits and six qi of birth date and the risk of type 2 diabetes mellitus(T2DM)incidence as well as the role and mechanism of the five circuits and six qi on T2DM incidence,thus to provide an objective evidence for the clinical application of the theory of the five circuits and six qi in the prevention and treatment of T2DM.Methods A univariate case-control study was carried out in 3332 outpatients and inpatients admitted to the four third-grade class-A hospitals of the First Affiliated Hospital of Guangzhou University of Chinese Medicine,Guangdong Provincial Hospital of Integrated Traditional Chinese and Western Medicine,Guangdong Second Traditional Chinese Medicine Hospital,and Foshan Hospital of Traditional Chinese Medicine from October 2020 to January 2022.Among them,2012 cases of T2DM were allocated to T2DM group and 1320 cases of non-T2DM were allocated to non-T2DM group.The age,gender,and birth date of the patients in the two groups were collected,and then the attributes of the birth date of each patient to suiyun(yearly evolutive phase),zhuyun(regular yearly evolutive phase),keyun(alternative yearly evolutive phase),sitian(the first half of the alterable yearly circuit qi),zaiquan(the second half of the alterable yearly circuit qi),zhuqi(regular yearly circuit qi),keqi(alternative yearly circuit qi),yunqitonghua(the year with yearly evolutive phase adaptive to yearly circuit qi),and kezhujialin(combination of zhuqi and keqi)were deduced through the method of circuits and qi.Statistical methods such as non-parametric test and chi-square test were used to explore the relationship between the attributes of the five circuits and six qi of the birth date and the risk of the incidence of T2DM.Results(1)No statistically significant differences were shown in the age and gender between the T2DM group and the non-T2DM group(P>0.05).(2)In the distribution of suiyun,the percentage of taijin(yearly evolutive phase with excess gold)in the T2DM group(14.17%)was higher than that in the non-T2DM group(11.14%),and the difference was statistically significant(P<0.05),while the distribution of the other suiyun attributes was not statistically significant between the two groups(P>0.05).(3)In the distribution of the pair of sitian and zaiquan,the percentage of taiyang-taiyin in the T2DM group(19.53%)was significantly higher than that in the non-T2DM group(16.21%),and the difference was statistically significant(P<0.05).However,the differences were not statistically significant in the distribution of the rest five pairs of sitian-zaiquan between the two groups(P>0.05).(4)In terms of the distribution of the attributes of zhuyun,keyun,zhuqi,keqi,yunqitonghua,and kezhujialin,there was no statistically significant difference between the two groups(P>0.05).Conclusion The attributes of the five circuits and six qi at birth that could increase the risk of the incidence of T2DM are the taijin of suiyun,the taiyang cold-water of sitian,and taiyang damp-earth of zaiquan.In addition,the taihuo(regular yearly evolutive phase with excess fire)of zhuyun,yangming dryness-mental of keqi,and zhuqi restricting keqi of kezhujialin may increase the risk of T2DM incidence,but it is not confirmed yet.The attributes of keyun,zhuqi,yunqitonghua have no influences on increasing the risk of T2DM incidence.It is not indicated that any attributes of the five circuits and six qi at birth will decrease the risk of T2DM incidence.