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肠道微生态治疗与孤独症的研究进展

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摘要 孤独症是一种神经发育性疾病,临床上以行为刻板,兴趣狭隘及社交障碍为核心表现,患病率在1%~2%,目前病因尚不明确,暂无有效的治疗方案,是影响儿童行为的重要疾病之一。流行病学研究发现,孤独症患儿更容易伴发不同程度的胃肠道症状,包括腹痛、腹泻、便秘、消化不良等,其肠道微生态失衡被证实是疾病发生的重要机制之一,认为其是环境因素作用于易感个体的内在表现。
出处 《重庆医学》 CAS 2023年第S02期184-186,共3页 Chongqing medicine
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  • 1Guarner F, Maiagelada JR. Gut flora in health and disease[J]. Lancet, 2003, 361(9356): 512-519.
  • 2Eckburg PB, Bik EM, Bernstein CN, et al. Diversity of the human intestinal microbial flora [J]. Science, 2005, 308 (5728) : 1635-1638.
  • 3Borody TJ, Campbell J. Fecal microbiota transplantation: tech- niques, applications, and issues[J]. Gastroenterol Clin North Am, 2012, 41(4): 781-803.
  • 4Surawicz CM, Brandt LJ, Binion DG, et al. Guidelines for di- agnosis, treatment, and prevention of Clostridium difficile in- fections[J]. Am J Gastroenterol, 2013, 108 (4): 478-498. quiz 499.
  • 5Borody TJ, Warren EF, Leis S, et al. Treatment of ulcerative colitis using fecal bacteriotherapy[J]. J Clin Gastroenterol, 2003, 37(1) :42-47.
  • 6Vrieze A, Van Nood E, Holleman F, et al. Transfer of intes- tinal microbiota from lean donors increases insulin sensitivity in individuals with metabolic syndrome[J]. Gastroenterology, 2012, 143(4):913-916.
  • 7e7. Finegold SM, Molitoris D, Song Y, et al. Gastrointestinal mi- croflora studies in late-onset autism[J]. Clin Infect Dis, 2002, 35(Suppl 1) : $6-S16.
  • 8Kelly CR, Kahn S, Kashyap P, et al. Update on fecal microbiota transplantation 2015: Indications, methodologies, mechanisms, and outlook[J]. Gastroenterology, 2015, I49(1): 223-237.
  • 9Youngster I, Russell GH, Pindar C, et al. Oral, capsulized, frozen fecal microbiota transplantation for relapsing Clostridi- um difficile infection[J]. JAMA, 2014, 312(17) : 1772-1778.
  • 10Persky SE, Brandt LJ. Treatment of recurrent Clostridium dif- fieile-associated diarrhea by administration of donated stool di- rectly through a colonoscope[J]. Am J Gastroenterol, 2000, 95(11) : 3283-3285.

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