纳洛酮联合氨茶碱在小儿呼吸衰竭治疗过程中的临床效果

Clinical Effect of Naloxone Combined with Aminophylline in the Treat⁃ment of Respiratory Failure in Children

目的 针对小儿呼吸衰竭患儿实施纳洛酮联合氨茶碱治疗干预,研究其临床疗效以及应用价值。方法选取2022年6月—2023年6月甘肃省金昌市中心医院收治的60例小儿呼吸衰竭患儿。采用随机数表法分为研究组与参照组,各为30例。参照组给予纳洛酮治疗,观察组给予纳洛酮联合氨茶碱治疗,比较两组患儿的临床效果以及不良反应总发生率。结果研究组患儿的治疗总有效率(100.00%)明显高于参照组(70.00%),差异有统计学意义(χ^(2)=10.588,P<0.05)。研究组患儿的不良反应总发生率(10.00%)明显低于参照组(30.00%),差异有统计学意义(χ~=4.811,P<0.05)。结论 小儿呼吸衰竭患儿实施纳洛酮联合氨茶碱治疗干预能提高临床治疗效果,能够明显降低患儿的不良反应发生率。

Objective To study the clinical efficacy and application value of naloxone combined with aminophylline therapy for pediatric children with respiratory failure.Methods 60 pediatric children with respiratory failure admitted to Jinchang Central Hospital of Jinchang City,Gansu Province from June 2022 to June 2023 were selected as the study objects.They were divided into the study group and the reference group,with 30 cases in each group.The refer-ence group was given naloxone treatment,and the study group was given naloxone combined with aminophylline treat-ment.The clinical effect and the total rate of adverse reactions of the two groups were compared.Results The total ef-fective rate in the study group(100.00%)was significantly higher than that in the reference group(70.00%),and the difference was statistically significant(χ^(2)=10.588,P<0.05).The total rate of adverse reactions in the study group(10.00%)was significantly lower than that in the reference group(30.00%),and the difference was statistically signifi-cant(χ^(2)=4.811,P<0.05).Conclusion The intervention of naloxone combined with aminophylline in pediatric children with respiratory failure can improve clinical effect and can significantly reduce the incidence of complications.