多巴胺联合常规药物治疗小儿肺炎的效果分析

Effect Analysis of Dopamine Combined with Conventional Drugs in the Treatment of Pediatric Pneumonia

目的:探讨多巴胺联合常规药物治疗小儿肺炎的效果。方法:选取2020年10月—2023年1月铜仁市妇幼保健院收治的90例肺炎患儿作为研究对象,随机分为对照组及观察组,各45例。对照组给予常规药物治疗,观察组在对照组基础上给予多巴胺治疗。比较两组治疗效果。结果:观察组咳嗽、发热、气促、肺部湿啰音消失时间,胸片检查恢复正常时间,住院时间均短于对照组,差异有统计学意义(P<0.001)。治疗后,两组肿瘤坏死因子-α、超敏C反应蛋白、白细胞介素-6水平均低于治疗前,且观察组低于对照组,差异有统计学意义(P<0.05)。治疗后,两组用力肺活量、第1秒用力呼气容积、呼气峰值流速水平均高于治疗前,且观察组高于对照组,差异有统计学意义(P<0.05)。观察组治疗总有效率高于对照组,差异有统计学意义(P=0.007)。结论:多巴胺联合常规药物治疗小儿肺炎的效果显著,可促进患儿症状改善,缩短住院时间,降低炎性因子水平,改善肺功能。

Objective:To explore the effect of dopamine combined with conventional drugs in the treatment of pediatric pneumo⁃nia.Methods:A total of ninety children with pneumonia admitted to Tongren Maternal and Child Health Hospital from October 2020 to January 2023 were selected as the study objects and randomly divided into control group and observation group,with forty-five cases in each group.The control group was given conventional drug treatment,and the observation group was given do⁃pamine treatment on the basis of the control group.The therapeutic effect of the two groups was compared.Results:The disappear⁃ance time of cough,fever,shortness of breath and pulmonary moist rales,the recovery time of chest X-ray examination and the length of hospital stay in the observation group were shorter than those in the control group,the difference was statistically signifi⁃cant(P<0.001);After treatment,the levels of tumor necrosis factor-α,hypersensitive C-reactive protein and interleukin-6 in 2 groups were lower than before treatment,and the observation group was lower than the control group,with statistical significance(P<0.05);After treatment,forced vital capacity,forced expiratory volume in the first second and peak expiratory flow rate in 2 groups were higher than before treatment,and observation group was higher than control group,the difference was statistically sig⁃nificant(P<0.05);The total effective rate of the observation group was higher than that of the control group,the difference was sta⁃tistically significant(P=0.007).Conclusion:Dopamine combined with conventional drugs can improve the symptoms of children with pneumonia,shorten the length of hospital stay,reduce the level of inflammatory factors,and improve lung function.