中药熏洗联合口服、局部给药治疗霉菌性阴道炎的临床疗效

Clinical Effect of Fumigation and Washing with Traditional Chinese Medicine Combined with Oral and Local Administration in the Treatment of Fungal Vaginitis

目的:探讨中药熏洗联合口服、局部给药治疗霉菌性阴道炎的临床疗效。方法:选取2022年1—12月松桃苗族自治县民族中医院接诊的霉菌性阴道炎患者60例作为研究对象,随机数字表法分为观察组和对照组,各30例。观察组给予中药熏洗联合口服及局部给药;对照组给予常规西药治疗,仅口服及局部给药。观察两组症状评分、血清炎性因子水平及治疗总有效率。结果:治疗前,两组患者外阴瘙痒、外阴灼痛、白带增多评分比较,差异无统计学意义(P>0.05);治疗后,观察组患者外阴瘙痒、外阴灼痛、白带增多评分低于对照组,差异有统计学意义(P<0.05)。治疗前,两组患者血清炎性因子水平比较,差异无统计学意义(P>0.05);治疗后,观察组患者白细胞介素-6、肿瘤坏死因子-α低于对照组,γ干扰素高于对照组,差异有统计学意义(P<0.05)。观察组治疗总有效率(96.7%)高于对照组(86.7%),差异有统计学意义(P<0.05)。结论:中药熏洗联合口服及局部给药治疗霉菌性阴道炎在缓解症状、降低炎性因子水平和提高治疗总有效率方面均表现明显的优势。同时,该方案安全性好,可作为临床治疗霉菌性阴道炎的一种有效方法。

Objective:To explore the clinical effect of fumigation and washing combined with oral and local administration of traditional Chinese medicine in the treatment of fungal vaginitis.Methods:A total of sixty patients with fungal vaginitis admitted to Songtao Miao Autonomous County Hospital of Traditional Chinese Medicine for Nationalities from January to December 2022 were selected as the study objects,and were divided into observation group and control group by random number table method,with thirty cases in each group.The observation group was given traditional Chinese medicine fumigation combined with oral and local administration,and the control group was given conventional western medicine treatment,only oral and local administration.Symptom score,serum inflammatory factor level and total effective rate were observed.Results:Before treatment,there was no significant difference in scores of vulvar pruritus,vulvar burning pain and increased leucorrhea between 2 groups(P>0.05);After treatment,the scores of vulvar pruritus,vulvar burning pain and increased leucorrhea in observation group were lower than those in control group,and the differences were statistically significant(P<0.05);Before treatment,there was no significant difference in serum inflammatory factors between 2 groups(P>0.05);After treatment,interleukin-6 and tumor necrosis factor-αin observation group were lower than those in control group,and interferonγwas higher than those in control group,the difference was statistically significant(P<0.05);The total effective rate of observation group(96.7%)was higher than that of control group(86.7%),and the difference was statistically significant(P<0.05).Conclusion:Traditional Chinese medicine fumigation combined with oral and local administration in the treatment of fungal vaginitis has obvious advantages in alleviating symptoms,reducing the level of inflammatory factors and improving the total effective rate.At the same time,the scheme has good safety and can be used as an effective method for the clinical treatment of mycotic vaginitis.