枣柏砂苓汤治疗心脾两虚型失眠的临床研究

Clinical Study of Zaobaishaling Decoction Treating Insomnia with Deficiency of Heart and Spleen

目的:观察枣柏砂苓汤治疗心脾两虚型失眠的临床疗效。方法:选取2022年1月—2023年1月广州市越秀区东山街社区卫生服务中心收治的120例心脾两虚型失眠患者作为研究对象,按随机数字表法分为对照组和治疗组,各60例。对照组给予艾司唑仑片治疗,治疗组在对照组基础上给予枣柏砂苓汤加减治疗,两组治疗3个月后比较匹兹堡睡眠质量指数(PSQI)评分、中医证候评分以及临床疗效。结果:两组患者治疗后,治疗组总有效率高于对照组,差异有统计学意义(P<0.05)。两组患者治疗前PSQI评分比较,差异无统计学意义(P>0.05);治疗后,两组患者PSQI评分均较治疗前明显下降,且治疗组低于对照组,差异有统计学意义(P<0.05)。两组患者治疗前各项中医证候评分比较,差异无统计学意义(P>0.05);治疗后,两组患者中医证候评分均较治疗前明显下降,且治疗组低于对照组,差异有统计学意义(P<0.05)。结论:运用枣柏砂苓汤治疗心脾两虚型失眠,疗效显著,能有效改善患者睡眠质量及临床症状。

Objective:To observe the clinical effect of Zaobaishaling decoction on insomnia caused by deficiency of heart and spleen.Methods:A total of one hundred and twenty insomnia patients with heart and spleen deficiency treated in Guangzhou Yuexiu District Dongshan Street Community Health Service Center from January 2022 to January 2023 were selected as the study objects,and were divided into control group and treatment group by random number table method,with sixty cases in each group.The control group was treated with Esazolam tablets,and the treatment group was treated with Zaobaishaling decoction on the basis of the control group.Pittsburgh sleep quality index(PSQI)score,TCM syndrome score and clinical efficacy were compared between the two groups after 3 months of treatment.Results:After treatment,the total effective rate of the treatment group was higher than the control group 76.67%,the difference was statistically significant(P<0.05);There was no significant difference in PSQI scores between the two groups before treatment(P>0.05);After treatment,PSQI scores in both groups were significantly lower than before treatment(P<0.05),and the treatment group was lower than the control group,the difference was statistically significant(P<0.05);There was no significant difference in TCM syndrome scores between the two groups before treatment(P>0.05);After treatment,TCM syndrome scores in both groups were significantly lower than before treatment(P<0.05),and the treatment group was lower than the control group,the difference was statistically significant(P<0.05).Conclusion:Using Zaobaishaling decoction to treat insomnia with both deficiency of heart and spleen,the curative effect is remarkable,and it can effectively improve the sleep quality and clinical symptoms of patients.