氯胺酮复合丙泊酚在腹股沟斜疝手术患儿中的应用

Application of Ketamine combined with Propofol in children undergoing indirect inguinal hernia surgery

目的探讨氯胺酮复合丙泊酚在腹股沟斜疝手术患儿中的应用效果。方法选取2021年10月至2023年9月在济南市第八人民医院接受手术治疗的80例腹股沟斜疝患儿,以随机数字表法分为研究组(40例)与对照组(40例)。对照组采用氯胺酮维持麻醉,研究组采用氯胺酮复合丙泊酚维持麻醉,比较两组苏醒质量、躁动情况、血流动力学指标。结果研究组自主呼吸恢复时间、拔管时间、苏醒时间、复苏室停留时间短于对照组(P<0.05),Ramsay镇静评分高于对照组(P<0.05);研究组躁动发生率低于对照组(P<0.05);两组给药后5 min(T1)、给药后15 min(T2)的平均动脉压(MAP)低于术前(T0),心率(HR)高于T0(P<0.05),但研究组T1、T2的MAP高于对照组(P<0.05),HR低于对照组(P<0.05)。结论氯胺酮复合丙泊酚应用于腹股沟斜疝手术患儿能够提高苏醒质量,降低躁动发生率,稳定血流动力学指标,值得推广。

Objective To explore the application effect of Ketamine combined with Propofol in children undergoing indirect inguinal hernia surgery.Methods A total of 80 children who underwent indirect inguinal hernia surgery in Jinan Eighth People’s Hospital from October 2021 to September 2023 were selected and divided into study group(40 cases)and control group(40 cases)by the random number table method.The control group was given Ketamine to maintain anesthesia,and the study group was given Ketamine combined with Propofol to maintain anesthesia.The recovery quality,agitation and hemodynamics indicators were compared between the two groups.Results The recovery time of spontaneous respiration,extubation time and recovery time in the study group were earlier than those in the control group,and the resuscitation room stay time in the study group was shorter than that in the control group(P<0.05),the ramsay sedation score in the study group was higher than that in the control group(P<0.05).The incidence of agitation in the study group was lower than that in the control group(P<0.05).The mean arterial pressure at 5 minutes after administration(T1)and 15 minutes after administration(T2)was lower than that before surgery(T0),and the heart rate was lower than that T0(P<0.05).However,the MAP at T1 and T2 in the study group was higher than that in the control group,and the HR was lower than that in the control group(P<0.05).Conclusion Ketamine combined with Propofol applied in children undergoing indirect inguinal hernia surgery can improve the quality of recovery,reduce the incidence of agitation,and stabilize the hemodynamic indicators,which is worth popularizing.