急诊血液灌注治疗百草枯急性中毒的临床效果

Clinical Effect Analysis of Emergency Hemoperfusion in Treatment of Acute Paraquat Poisoning

目的:分析急诊血液灌注治疗百草枯急性中毒的临床效果。方法:选取2018年3月—2022年3月滨州医学院附属医院收治的百草枯急性中毒患者62例作为观察对象,2018年3月—2020年11月进行常规治疗的患者31例为对照组,2020年12月—2022年3月进行血液灌注治疗的患者31例为观察组。比较两组患者治疗效果。结果:观察组急救成功率高于对照组,差异有统计学意义(P=0.036);治疗3周后,观察组肝功能障碍、肾功能障碍、中毒性心肌炎、多器官功能障碍综合征发生率低于对照组,死亡病例平均存活时间长于对照组,死亡率低于对照组,差异有统计学意义(P<0.05)。结论:百草枯急性中毒患者在急救过程中使用血液灌注治疗,能有效提高抢救成功率,提高治疗效果。

Objective:To analyze the clinical effect of emergency hemoperfusion in the treatment of acute paraquat poisoning.Methods:A total of 62 patients with acute paraquat poisoning admitted to Binzhou Medical University Hospital from March 2018 to March 2022 were selected as the observation objects.Among them,31 patients who underwent conventional treatment from March 2018 to November 2020 were selected as the control group,and 31 patients who underwent hemoperfusion therapy from December 2020 to March 2022 were selected as the observation group.The treatment effect of the two groups was compared.Results:The success rate of first aid in the observation group was higher than that in the control group,and the difference was statistically significant(P=0.036).After 3 weeks of treatment,the incidence of liver dysfunction,renal dysfunction,toxic myocarditis and multi-organ dysfunction syndrome in the observation group was lower than that in the control group,the average survival time of the death cases in the observation group was longer than that in the control group,and the mortality rate in the observation group was lower than that in the control group,and the difference was statistically significant(P<0.05).Conclusion:The use of hemoperfusion therapy in emergency treatment of acute paraquat poisoning patients can effectively increase the success rate of rescue and improve the curative effect.