2017—2021年蚌埠市儿童碘营养状况及甲状腺容积影响因素分析

Analysis of iodine nutrition status and factors affecting the thyroid volume of children in Bengbu from 2017 to 2021

目的分析蚌埠市儿童碘营养状况和甲状腺容积影响因素,为蚌埠市儿童科学合理的补碘措施提供理论指导和数据支持。方法蚌埠市7个地区随机抽取7000名儿童,进行尿碘含量检测,甲状腺、身高和体重检查。结果不同年份、不同地区、不同性别间儿童尿碘水平存在统计学差异(P<0.001),不同年龄学生尿碘水平差异没有统计学意义(P>0.05)。不同地区儿童甲状腺容积差异有统计学意义(H=92.101,P<0.001),不同地区儿童甲状腺肿大率差异没有统计学意义(P>0.005)。儿童尿碘浓度水平和体质指数(BMI)、体表面积(BSA)、地区存在正相关,与年龄、性别不存在相关。儿童甲状腺容积和尿碘、年龄、BMI、BSA存在正相关。影响儿童甲状腺容积的独立因素有尿碘、年龄、BSA,影响因素由大至小依次是BSA、年龄、尿碘。结论总体儿童甲状腺肿大率处于较低水平,总体碘营养为超适宜量水平,但存在儿童缺碘和碘过量问题。影响蚌埠市儿童甲状腺容积的最大独立因素是BSA。

Objective To analyze the factors affecting iodine nutrition status and thyroid volume of children in Bengbu City,so as to provide theoretical guidance and data support for scientific and reasonable iodine supplement measures for children in Bengbu City.Methods A total of 7000 children were randomly selected from 7 areas in Bengbu City for urine iodine content detection,thyroid,height and weight examination.Results There were statistically significant differences in urinary iodine level among children in different years,regions and genders(P<0.001),but no statistically significant differences in urinary iodine level among students of different ages(P>0.05).There was statistical significance in thyroid volume of children from different regions(H=92.101,P<0.001),but there was no statistical significance in goiter rate of children from different regions(P>0.005).Urinary iodine concentration in children was positively correlated with BMI,BSA and region,but not with salt iodine,age and sex.Thyroid volume was positively correlated with urinary iodine,age,BMI and BSA in children.The independent factors affecting thyroid volume in children were age,urinary iodine and BSA,and the influencing factors were BSA,age,and urinary iodine in descending order.Conclusion The overall goiter rate of children is at a low level,and the overall iodine nutrition is above the appropriate level,but there are iodine deficiency and iodine excess problems in children.BSA is the biggest independent factor affecting the thyroid volume of children in Bengbu City.