微创保胆取石术治疗胆结石的临床疗效及对患者疼痛的影响

Clinical effect of minimally invasive gallstone-preserving lithotomy and its effect on pain of patients with gallstones

目的探讨微创保胆取石术治疗胆结石的临床疗效及对患者疼痛的影响。方法选取2019年4月至2020年4月邹城市人民医院收治的100例胆结石患者作为研究对象,按照随机数字表法分为对照组与观察组,每组50例。对照组行腹腔镜胆囊切除术,观察组行微创保胆取石术,比较两组胃肠功能、围手术期指标、消化病生存质量指数(GLQI)评分、视觉模拟评分法(VAS)评分、并发症发生情况。结果术后,两组胃动素水平均高于术前,胃泌素水平均低于术前,且观察组胃动素水平高于对照组,胃泌素水平低于对照组,差异有统计学意义(P<0.05)。观察组术中出血量少于对照组,手术时间、排气时间、住院时间均短于对照组,差异有统计学意义(P<0.05)。术后6个月,两组GLQI评分均高于术后1个月,且观察组高于对照组,差异有统计学意义(P<0.05)。术后3 d,两组VAS评分均低于术前,且观察组低于对照组,差异有统计学意义(P<0.05)。观察组并发症发生率为2.00%,低于对照组的14.00%,差异有统计学意义(P<0.05)。结论微创保胆取石术治疗胆结石疗效显著,可提高患者GLQI评分,改善临床指标,且能降低术后VAS评分,安全性较高,值得临床推广应用。

Objective To investigate the clinical effect of minimally invasive gallstone-preserving lithotomy and its effect on pain in patients with gallstones.Methods 100 patients with gallstones admitted to Zoucheng People's Hospital from April 2019 to April 2020 were selected as the study subjects,and they were divided into the control group and the observation group according to the random number table method,with 50 cases in each group.The control group underwent laparoscopic cholecystectomy,and the observation group underwent minimally invasive gallbladder-pre-serving lithotomy,the gastrointestinal function,perioperative indicators,digestive disease quality of life index(GLQI),visual analogue scale(VAS)score,and complications were compared between the two groups.Results After operation,the levels of motilin of the two groups were higher than those before operation,and the levels of gastrin were lower than those before operation,and the level of motilin in the observation group was higher than that in the control group,and the level of gastrin was lower that those in the control group,the differences were statistically significant(P<0.05).The intraoperative blood loss in the observation group was less than that in the control group,and the operation time,exhaust time and hospital-ization time were shorter than those in the control group,the differences were statistically significant(P<0.05).At 6 months after operation,the GLQI scores of the two groups were higher than those at 1 month after operation,and the observation group was higher than the control group,the differenc-es were statistically significant(P<0.05).At 3 d after operation,the VAS scores of the two groups were lower than those before operation,and the ob-servation group was lower than the control group,the differences were statistically significant(P<0.05).The incidence of complications in the obser-vation group was 2.00%,which was lower than 14.00%in the control group,the difference was statistically significant(P<0.05).Conclusion Mini-mally invasive gallbladder-preserving lithotomy is effective in the treatment of gallstones,it can improve GLQI score,improve clinical indicators,and reduce postoperative VAS score,it is safe and worthy of clinical promotion and application.