从“以补为通”理论探讨补益药治疗老年动脉粥样硬化

Treatment of Senile Atherosclerosis with Tonics From Theory of"Yi Bu Wei Tong"

动脉粥样硬化好发于老年人群,衰老作为其重要的危险因素在临床治疗时不可忽视。中医认为,衰老可归因于脏腑气血阴阳亏虚,多表现为虚证,治疗宜使用补益类药物,佐以活血、祛痰、清热、化湿等药物全面施治。“以补为通”理论源于“塞因塞用,以补开塞”,指用补益的方法治疗闭塞不通的真虚假实证,此处的以补为通,还另指使用补益的方法治疗缓解期的本虚标实与虚实夹杂之证。补益药可以通过提高抗氧化物活力、促进自由基岐化、直接中和自由基来抑制自由基的产生,维持机体抗氧化系统的平衡,从而实现抗衰老。

Atherosclerosis tends to occur in the elderly,and aging,as an important risk factor,cannot be ignored in clinical treatment.In traditional Chinese medicine it is believed that aging can be attributed to the deficiency of organs,Qi,blood,Yin and Yang,which is often manifested as deficiency syndrome.In treatment,tonifying drugs,accompanied by comprehensive treatment with drugs such as promoting blood circulation,eliminating Phlegm,clearing Heat and dispelling Dampness should be used.The theory of"Yi Bu Wei Tong"originates from the concept of"Sai Yin Sai Yong,Yi Bu Kai Sai",which refers to the use of tonifying methods to treat the deficiency syndrome,actually,the false excess syndrome of occlusive obstruction.Here,it also refers to the use of tonifying methods to treat the syndrome of the combination of deficiency and excess in the relief period.Tonifying drugs can inhibit the production of free radicals,maintain the balance of the body′s antioxidant system,and thus achieve anti-aging by enhancing antioxidant activity,promoting free radical dismutation and directly neutralizing free radicals.