摘要
肌少—骨质疏松症是一种肌少症和骨质疏松症并存的老年综合征。发病机制涉及遗传基因、骨骼-肌肉机械作用、内分泌调节机制、分子信号通路等多种因素。在临床实践中,除了需综合评估危险因素外,还需筛查骨密度、肌肉力量、肌肉质量及机体整体功能情况。干预措施主要包括运动疗法、营养支持和药物等。
Osteosarcopenia is a geriatric syndrome referring to the co-existence of osteoporosis and sarcopenia.Its pathogenesis involves factors such as genetics,mechanics of the musculoskeletal system,endocrine regulatory mechanisms and molecular signaling pathways.In clinical practice,aside from comprehensive assessment of risk factors,screening of bone density,muscle strength,muscle mass and the overall body function must also be undertaken.Intervention measures primarily include therapeutic exercise,nutritional support and drugs.
作者
李悦芃
董娟
张任飞
陈璐
邱蕾
Li Yuepeng;Dong Juan;Zhang Renfei;Chen Lu;Qiu Lei(Department of Health Care,Beijing Hospital,National Center of Gerontology Institute of Geriatric Medicine,Chinese Academy of Medical Sciences,Beijing 100730,China)
出处
《中华老年医学杂志》
CAS
CSCD
北大核心
2024年第1期77-81,共5页
Chinese Journal of Geriatrics
关键词
骨质疏松
肌骨骼疾病
治疗
Osteoporosis
Musculoskeletal diseases
Therapy