摘要
目的 研究临床治疗子宫内膜息肉采取宫腔镜联合屈螺酮炔雌醇的效果与价值。方法 随机选取2020年3月—2023年6月如皋市人民医院妇产科收治的子宫内膜息肉患者130例作为研究对象,根据随机抽签法分为对照组、观察组,每组65例。两组均接受宫腔镜手术治疗,对照组术后服用黄体酮,观察组术后服用屈螺酮炔雌醇。观察且对比两组临床疗效,治疗前后激素水平,内膜厚度、月经量变化,不良反应发生情况。结果 观察组总有效率为98.46%,高于对照组,差异有统计学意义(χ^(2)=6.933,P<0.05)。同时治疗后观察组激素水平、内膜厚度均低于对照组,月经量少于对照组,差异有统计学意义(P<0.05)。治疗后两组不良反应发生率比较,差异无统计学意义(P>0.05)。结论 临床治疗子宫内膜息肉疾病可在宫腔镜手术基础上联用屈螺酮炔雌醇药物,能够提高疗效,调节激素水平,减少月经量,且不增加不良反应。
Objective To study the effect and value of hysteroscopy combined with drospiroone ethinylestradiol in clinical treatment of endometrial polyps.Methods A total of 130 patients with endometrial polyps admitted to the Ob-stetrics and Gynecology Department of Rugao People's Hospital from March 2020 to June 2023 were randomly se-lected as the study objects,and were divided into control group and observation group according to random drawing method,with 65 cases in each group.Both groups received hysteroscopic surgery,the control group received progester-one after surgery,and the observation group received drospirosterone after surgery.The clinical efficacy,hormone lev-els,intima thickness,menstrual volume and adverse reactions were observed and compared between the two groups.Results The total effective rate of the observation group was 98.46%,higher than that of the control group,and the dif-ference was statistically significant(χ^(2)=6.933,P<0.05).At the same time,after treatment,the hormone level and in-tima thickness of the observation group were lower than that of the control group,and the menstrual volume was lower than that of the control group,the differences were statistically significant(P<0.05).There was no statistically signifi-cant difference in the incidence of adverse reactions between the two groups after treatment(P>0.05).Conclusion Clinical treatment of endometrial polyp disease can be based on hysteroscopic surgery combined with drospiroone ethi-nylestradiol,which can improve the curative effect,regulate hormone levels,reduce menstrual volume,and do not in-crease adverse reactions.
作者
钱进
殷美琴
王永霞
QIAN Jin;YIN Meiqin;WANG Yongxia(Department of Obstetrics and Gynecology,Rugao People's Hospital,Rugao,Jiangsu Province,226500 China)
出处
《中外医疗》
2023年第34期80-83,共4页
China & Foreign Medical Treatment
关键词
屈螺酮炔雌醇
子宫内膜息肉
内膜厚度
促黄体生成素
Drospiroone ethinylestradiol
Endometrial polyps
Intimal thickness
Luteinizing hormone