整肠散穴位贴敷在慢性阻塞性肺疾病急性加重期无创通气并发腹胀患者中的应用效果

Application effect of Zhengchang San acupoint application in patients with abdominal distension due to non-invasive ventilation during acute exacerbation of chronic obstructive pulmonary disease

目的 研究整肠散穴位贴敷在慢性阻塞性肺疾病急性加重期(AECOPD)无创通气并发腹胀患者中的临床治疗效果。方法 选取120例行无创通气住院诊治的慢性阻塞性肺疾病急性加重期患者作为研究对象,随机分为对照组和研究组,每组60例。对照组患者给予常规治疗,研究组患者在对照组基础上使用整肠散进行穴位贴敷。对比两组患者临床疗效,治疗前后胃肠道症状评定量表(GSRS)评分、腹围及腹内压水平。结果 所有患者均顺利完成研究,无不良反应发生。研究组中52例显效, 6例有效, 2例无效,总有效率为96.67%;对照组中27例显效, 24例有效, 9例无效,总有效率为85.00%;研究组总有效率显著高于对照组,差异具有统计学意义(P<0.05)。治疗前,两组患者的GSRS评分、腹围及腹内压水平对比差异无统计学意义(P>0.05);治疗后,两组患者GSRS评分、腹围及腹内压均低于治疗前,且研究组患者的GSRS评分(15.80±1.52)分、腹围(89.48±5.76)cm及腹内压(2.38±0.83)mm Hg(1 mm Hg=0.133 kPa)均低于对照组的(18.90±2.43)分、(95.26±4.14)cm、(3.05±1.10)mm Hg,差异具有统计学意义(P<0.05)。结论 使用整肠散穴位贴敷可改善慢性阻塞性肺疾病急性加重期无创通气并发腹胀患者的胃肠道症状,促进排气,减轻腹胀,减少腹围,降低腹内压,可接受程度高,具有较高的临床价值,值得推广。

Objective To study the clinical therapeutic effect of Zhengchang San acupoint application in patients with abdominal distension due to non-invasive ventilation during acute exacerbation of chronic obstructive pulmonary disease(AECOPD).Methods A total of 120 patients with acute exacerbation of chronic obstructive pulmonary disease who were hospitalized for non-invasive ventilation were selected as the study subjects.They were randomly divided into a control group and a study group,with 60 cases in each group.Patients in the control group were given conventional treatment,and patients in the study group were treated with Zhengchang San acupoint application on the basis of the control group.The clinical efficacy,gastrointestinal symptom rating scale(GSRS)score,abdominal circumference and intra-abdominal pressure before and after treatment were compared between the two groups.Results All patients successfully completed the study without adverse reactions.In the study group,52 cases were significantly effective,6 cases were effective,2 cases were ineffective,and the total effective rate was 96.67%.In the control group,27 cases were significantly effective,24 cases were effective,9 cases were ineffective,and the total effective rate was 85.00%.The total effective rate of the study group was significantly higher than that of the control group,and the difference was statistically significant(P<0.05).Before treatment,there was no statistically significant difference in GSRS score,abdominal circumference and intra-abdominal pressure between the two groups(P>0.05).After treatment,GSRS score,abdominal circumference and intra-abdominal pressure in both groups were lower than those before treatment in this group;in the study group,GSRS score was(15.80±1.52)points,the abdominal circumference was(89.48±5.76)cm and the intra-abdominal pressure was(2.38±0.83)mm Hg(1 mm Hg=0.133 kPa),which were lower than those of(18.90±2.43)points,(95.26±4.14)cm and(3.05±1.10)mm Hg in the control group;the differences were statistically significant(P<0.05).Conclusion The application of Zhengchang San at acupoint application can improve the gastrointestinal symptoms of patients with abdominal distension due to non-invasive ventilation during acute exacerbation of chronic obstructive pulmonary disease,promote exhaust gas,reduce abdominal distension,reduce abdominal circumference,and reduce intra-abdominal pressure.The acceptability is high,and it has high clinical value,and is worth popularizing.