乌梅丸研究热点和前沿可视化分析

Visualization Analysis on Research Hotspots and Frontier of Wumei Pills

目的梳理乌梅丸相关研究文献,了解该领域研究现状及热点,为后续研究提供参考。方法检索中国知识资源总库(CNKI)、中文科技期刊数据库(VIP)、中国学术期刊数据库(万方数据)、中国生物医学文献数据库(CBM)建库至2023年1月12日发表的乌梅丸相关文献。采用NoteExpress3.0软件管理题录信息,提取发表时间、作者、作者单位、关键词等信息并进行预处理,采用VOSviewer1.6.18软件对作者、作者单位、关键词进行共现和聚类分析,构建关键词时间叠加网络并对其进行可视化分析。结果经筛选,纳入文献2105篇,涉及闫曙光、范恒、惠毅等3554位作者,来自北京中医药大学东直门医院、山东中医药大学、北京中医药大学等1135个研究机构。纳入文献包含关键词2565个,共出现7061次,研究涉及4个主要研究方向:消化系统疾病(溃疡性结肠炎)、中医经典研究(《伤寒杂病论》)、医案经验和胆道蛔虫病。近年来乌梅丸研究热点较为分散,六经病欲解时、开阖枢、肠道菌群、炎性因子、失眠等为近3年研究热点。结论乌梅丸相关研究多集中于消化系统疾病、中医经典研究、医案经验和胆道蛔虫病四部分,中医理论研究及作用机制研究方向为该领域研究前沿热点。

Objective To summarize the research status and hotspots of Wumei Pills;To provide ideas and methods for the follow-up research of Wumei Pills.Methods Related literature about Wumei Pills was retrieved from CNKI,VIP,Wanfang Data and CBM from the establishment of the databases to January 12,2023.The publication time,author,author unit and keywords were collected and extracted through NoteExpress 3.0 software to manage bibliographic data.VOSviewer 1.6.18 software was used to conduct co-occurrence and clustering analysis,and construct keyword time superposition network.Results After screening,a total of 2105 articles were included,involving 3554 authors,such as Yan Shuguang,Fan Heng,and Hui Yi.They were from 1135 units,such as Dongzhimen Hospital of Beijing University of Chinese Medicine,Shandong University of Traditional Chinese Medicine and Beijing University of Chinese Medicine.The included articles contained 2565 keywords,which appeared 7061 times,and the research involved 4 main directions:digestive system diseases(ulcerative colitis),study on TCM classics(Shang Han Za Bing Lun),medical cases and experience,and biliary ascariasis.The hotspots of Wumei Pills were scattered in recent years.Six meridian disease to appear,opening and closing pivots,intestinal microbiota,serum inflammatory factors and insomnia were research hotspots in recent 3 years.Conclusion The research of Wumei Pills mainly focus on the research of digestive system diseases,TCM classics,medical cases and experience,and biliary ascariasis.Theoretical research of TCM and mechanism research possibly become new hotspots of this field.