能量负平衡影响奶牛卵泡发育的机制

Mechanisms of Negative Energy Balance Affects Follicular Development in Dairy Cattle

奶牛能量负平衡(negative energy balance,NEB)是奶牛产后泌乳初期常会发生的一种代谢性疾病,当奶牛摄入能量无法满足其消耗能量时就会达到NEB状态。奶牛处于NEB状态时易引起患病率增加、妊娠率降低、生产性能下降,给集约化奶牛生产带来很大的经济损失。随着分子、组学技术的广泛应用,奶牛泌乳初期NEB对牛卵泡发育的影响机制得到进一步揭示。本文根据近年来相关报道,综述奶牛早期泌乳NEB对牛卵泡发育分子机制相关研究进展并进行展望,以期为减少NEB对奶牛繁殖性能的不利影响提供理论参考。

Negative energy balance(NEB)is a metabolic disease which often occurs in cows during the early postpartum lactation period,and the NEB status will be reached when the energy intake is not sufficient to meet the energy consumption.Cows in NEB status leads to the increase of cow disease rate,decrease of pregnancy rate,and decrease of production performance,which brings great economic losses to intensive dairy production.With the wide application of molecular and histological techniques,the mechanism of NEB effect on bovine follicular development in early lactation of cows has been further revealed.This paper reviewed the research progress related to the molecular mechanism of NEB on bovine follicular development in early lactation of dairy cows according to the studies in recent years and made an outlook,aiming to provide reference for the theory of reducing the adverse effects of NEB on the reproductive performance of dairy cows.