抗菌肽调节动物肠道健康研究进展

Research progress of antimicrobial peptides in regulating animal intestinal health

肠道健康关系着畜禽的整体健康和生产性能,对于降本增效、改善饲料报酬至关重要。由于国家禁抗减抗政策的实施,抗菌肽、酸化剂、植物精油等在畜牧业领域开始发挥越来越重要的作用。抗菌肽是由动植物本身产生的一种生物活性肽,具有抗菌、抗病毒、抗氧化、调节免疫等多种生物学功能,近年来,关于抗菌肽调节动物肠道健康的研究也越来越广泛。本文主要对国内外关于抗菌肽调节动物肠道健康的研究进展进行总结,从抗菌肽调节肠道炎症损伤、菌群组成、形态结构、消化吸收、免疫屏障等方面系统阐述其改善肠道健康的作用机制,为抗菌肽应用于畜牧养殖业中发挥减抗替抗、降本增效的作用提供借鉴和参考。

Gut health is related to the overall health and production performance of livestock and poultry.It is essential to reduce costs and increase efficiency and improve feed returns.Antimicrobial peptides,acidifiers and plant essential oils have begun to play an increasingly important role in the field of animal husbandry by the implementation of the national policy of prohibiting and reducing antibiotics.Antimicrobial peptides are bioactive peptides produced by animals and plants themselves,have various biological functions such as antibacterial,antiviral,antioxidant and immune regulation.In recent years,research on antimicrobial peptides to modulate animal gut health is also increasingly widespread.This paper mainly summarized the latest research on the regulation of animal intestinal health by antimicrobial peptides at home and abroad.The mechanism of antimicrobial peptides to improve intestinal health was systematically expounded from the aspects of antimicrobial peptides regulating intestinal inflammatory damage,microflora composition,morphological structure,digestion and absorption,immune barrier,etc.,to provide reference for the application of antimicrobial peptides in animal husbandry to reduce or replace antibiotics,reduce cost and increase efficiency.