孕晚期胎儿胸腺参数与孕周的相关性分析

Correlation Analysis between Fetal Thymus Parameters and Gestational Age Measured

【目的】探讨孕晚期胎儿胸腺参数与孕周的相关性。【方法】选择2022年1月至2023年1月在西北大学第一医院进行产检的200例孕晚期孕妇为研究对象,其中孕29~31周48例,32~34周43例,35~37周54例,38~40周55例。所有孕妇均进行二维及三维超声检查,分别于三血管切面、左无名静脉切面测量胎儿胸腺前后径、横径、周长、横断面积,并通过三维容积成像测量胸腺体积。比较不同孕周胎儿胸腺前后径、横径、周长、横断面积、体积;采用Pearson相关系数分析胸腺前后径、横径、周长、横断面积、体积与孕周的相关性。【结果】29~31周、32~34周、35~37周、38~40周胎儿三血管切面、左无名静脉切面所测胸腺前后径、横径、周长、横断面积依次上升,且组间比较,差异有统计学意义(P<0.05);29~31周、32~34周、35~37周、38~40周胎儿胸腺体积依次上升,且组间比较,差异有统计学意义(P<0.05)。Pearson相关系数分析结果显示:胸腺前后径、横径、周长、横断面积、体积与孕周均呈正相关(P<0.05)。【结论】孕晚期胎儿胸腺前后径、横径、周长、横断面积、体积随孕周增长而上升,且胸腺前后径、横径、周长、横断面积、体积与孕周均呈正相关。

【Objective】To investigate the correlation between fetal thymus parameters and gestational age in the third trimester.【Methods】From January 2022 to January 2023,200 pregnant women in the third trimester were selected from Northwestern University First Hospital,of which 48 were from 29 to 31 weeks,43 were from 32 to 34 weeks,54 were from 35 to 37 weeks,and 55 were from 38 to 40 weeks.All pregnant women underwent two-and three-dimensional ultrasonography to measure the anterior and posterior diameter,transverse diameter,circumference and transverse area of fetal thymus at the section of three vessels and the section of left innominate vein,respectively,and the volume of thymus was measured by three-dimensional volumetric imaging.The diameter,transverse diameter,circumference,transverse area and volume of thymus in different gestational weeks were compared.Pearson correlation coefficient was used to analyze the relationship of gestational age with anterior and posterior diameter,transverse diameter,circumference,transverse area and volume of thymus.【Results】The anterior and posterior diameter,transverse diameter,circumference and transverse area of thymus measured at the section of the three blood vessels and the section of the left innominate vein at weeks 29 to 31,32 to 34,35 to 37 and 38 to 40 increased sequentially,and the differences between groups were statistically significant(P<0.05).The volume of fetal thymus from 29 to 31 weeks,32 to 34 weeks,35 to 37 weeks and 38 to 40 weeks increased in sequence,and the differences between groups were statistically significant(P<0.05).Pearson correlation coefficient analysis showed that the anterior and posterior diameter,transverse diameter,circumference,transverse area and volume of thymus were positively correlated with gestational age(P<0.05).【Conclusion】The anteroposterior diameter,transverse diameter,circumference,transverse area and volume of thymus increased with the increase of gestational weeks,and the anteroposterior diameter,transverse diameter,circumference,transverse area and volume of thymus were positively correlated with gestational week.