氨茶碱与多索茶碱在支气管哮喘治疗中的作用

The Role of Aminophylline and Doxthelline in the Treatment of Bronchial Asthma

目的研究在支气管哮喘治疗中采取氨茶碱与多索茶碱的应用效果。方法选择莆田市涵江医院支气管哮喘治疗患者100例,为患者均实施抽签法分组,分为观察组、对照组,观察组对于患者实施多索茶碱治疗,对照组对于患者实施氨茶碱治疗,比较两组治疗有效率、临床症状消失时间、治疗前后血清炎性因子水平、肺功能指标、血气分析指标、不良反应发生率。结果观察组治疗有效率、肺功能各项指标均高于对照组(均P<0.05);观察组临床症状消失时间短于对照组(均P<0.05);治疗后,观察组血清炎性因子水平、不良反应发生率均低于对照组(均P<0.05);治疗后,观察组血气分析指标PaO_(2)水平高于对照组,PaCO_(2)水平低于对照组(均P<0.05)。结论多索茶碱治疗应用在支气管哮喘中效果显著,有利于帮助患者改善肺功能,减少不良反应的发生。

Objective To study the effect of aminophylline and doxophylline in the treatment of bronchial asthma.Methods Selected Putian Hanjiang Hospital bronchial asthma treatment patients 100 cases,for the patients are implemented for the lottery method grouping,divided into the observation group,the control group,the observation group for the patients to implement doxophylline treatment,the control group for the patients to implement aminophylline treatment,comparing the two groups of effective rate of treatment,the time of the disappearance of clinical symptoms,before and after the treatment of the level of serum inflammatory factor,pulmonary function indicators,blood gas analysis indicators,the incidence of adverse reactions.Results The treatment efficiency and lung function indexes of the observation group were higher than those of the control group(all P<0.05);the disappearance time of clinical symptoms of the observation group was shorter than that of the control group(all P<0.05);after the treatment,the serum inflammatory factor level and the incidence rate of adverse reactions of the observation group were lower than those of the control group(all P<0.05);after the treatment,the PaO_(2) level of the observation group was higher than that of the control group,and PaCO_(2) level was lower than that of the control group(all P<0.05).Conclusions The therapeutic application of doxophylline is effective in bronchial asthma,which is conducive to helping patients improve lung function and reduce the occurrence of adverse effects.