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预测NSTEMI病人冠状动脉内血栓类型列线图模型的构建 被引量:1

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摘要 目的:应用光学相干断层扫描(OCT)研究急性非ST段抬高型心肌梗死(NSTEMI)病人冠状动脉内血栓的特征,并构建出预测NSTEMI病人冠状动脉内血栓类型的列线图模型。方法:连续纳入2021年5月—2022年2月接受急诊冠脉造影并在急诊冠状动脉治疗期间接受OCT检查的62例NSTEMI病人,根据OCT下血栓的特点,将入选的62例NSTEMI病人分为白色血栓组和红色/混合血栓组,比较两组病人的血栓特征和临床特征。采用两个独立样本t检验或χ^(2)检验筛选出预测因素,使用多因素Logistic回归分析NSTEMI冠状动脉内血栓类型的独立预测因素。以独立预测因素为基础构建出预测NSTEMI病人冠状动脉内血栓类型的列线图模型。使用Bootstrap法进行模型内部验证,绘制校准曲线,评价模型的校准度;绘制受试者工作特征(ROC)曲线,评估列线图模型预测NSTEMI病人冠状动脉内血栓类型的效能。结果:白色血栓组37例(59.7%),红色/混合血栓组25例(40.3%)。多因素Logistic回归分析显示,缺血时间、三支病变、闭塞病变、梗死相关血管侧支循环是NSTEMI病人冠状动脉内血栓类型的独立预测因素,以此构建出列线图模型,ROC曲线下面积(AUC)是0.941,校正曲线显示,预测结果与实际结果有较好的一致性。结论:以冠状动脉三支病变、非闭塞病变、梗死相关血管侧支循环、缺血时间等构建的列线图模型可直观、便捷、有效预测NSTEMI病人冠状动脉内血栓类型。
出处 《中西医结合心脑血管病杂志》 2024年第3期536-542,共7页 Chinese Journal of Integrative Medicine on Cardio-Cerebrovascular Disease
基金 河南省重点科技攻关计划项目(No.122102310068)。
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