微创锥颅软通道置管引流对高血压脑出血患者NIHSS评分及生活质量的影响

The effect of minimally invasive intracranial soft channel drainage on NIHSS score and quality of life in patients with hypertensive intracerebral hemorrhage

目的分析微创锥颅软通道置管引流对高血压脑出血患者神经功能缺损程度(NIHSS)评分及生活质量的影响。方法纳入2021年3月-2022年10月泰州市第二人民医院收治的高血压脑出血患者86例为研究对象,根据治疗方式不同分为两组,对照组43例采用常规开颅血肿清除术治疗,观察组43例采用微创锥颅软通道置管引流术治疗,对比两组NIHSS评分、手术情况、血肿清除率、并发症发生情况以及血清神经元特异性烯醇化酶(NSE)、中枢神经特异蛋白(S100β)变化情况。结果观察组手术时间、血肿引流时间、住院时间均短于对照组,并且血肿清除率高于对照组(P<0.05);治疗后7d观察组NIHSS评分及NSE、S100β水平均低于对照组(P<0.05);观察组并发症发生率低于对照组,生活质量评分高于对照组(P<0.05)。结论高血压脑出血患者应用微创锥颅软通道置管引流术治疗具有创伤小、血肿清除率高的优势,能缩短血肿引流时间,减轻患者神经功能缺损程度,降低血清NSE、S100β水平,对其预后改善及生活质量提高有积极作用。

Objective To analyze the effect of minimally invasive craniotomy soft channel drainage on the score of neurological deficit(NIHSS)and quality of life in patients with hypertensive cerebral hemorrhage.Methods Eighty-six patients with hypertensive cerebral hemorrhage admitted to our hospital from March 2021 to October 2022 were divided into two groups according to different treatment methods.The control group(43 cases)was treated with conventional craniotomy and the observation group(43 cases)was treated with minimally invasive craniotomy and soft channel drainage.The NIHSS score,operation situation,hematoma clearance rate and complications,serum neuron-specific enolase(NSE)and central nervous system specificity were compared between the two groups.Results The operation time,hematoma drainage time and hospitalization time in the observation group were shorter than those in the control group,and the hematoma clearance rate was higher than that in the control group(P<0.05).7 days after treatment,the NIHSS score,NSE and S100βlevels in the observation group were lower than those in the control group(P<0.05).The complications in the observation group were lower than those in the control group,and the quality of life score was higher than that in the control group(P<0.05).Conclusion The application of minimally invasive craniotomy soft channel catheter drainage in patients with hypertensive cerebral hemorrhage has the advantages of less trauma and high hematoma clearance rate,which can shorten the hematoma drainage time,reduce the degree of neurological deficit of patients,and reduce the levels of serum NSE and S100β,which has a positive effect on improving their prognosis and quality of life.