活血通脉汤对子宫内膜息肉切除术患者的影响

Effect of Huoxue Tongmai Tang on patients undergoing endometrial polypectomy

目的探讨活血通脉汤对宫腔镜下子宫内膜息肉(EP)切除术患者的影响。方法选取2018年1月至2021年1月在该院行宫腔镜下EP切除术患者100例,按随机数字表法将其分为观察组和对照组,各50例。对照组口服去氧孕烯炔雌醇片,观察组口服活血通脉汤。比较2组治疗前后子宫内膜中雌激素受体(ER)、孕激素受体(PR)阳性率,以及月经量、经期时间、子宫内膜厚度、术后复发率与并发症发生情况。结果观察组治疗后子宫内膜中ER阳性率低于治疗前,PR阳性率高于治疗前,差异有统计学意义(P<0.05)。对照组治疗后子宫内膜中ER、PR阳性率与治疗前比较,差异无统计学意义(P>0.05)。观察组治疗后子宫内膜中ER阳性率低于对照组,PR阳性率高于对照组,差异有统计学意义(P<0.05)。2组治疗后月经量、经期时间、子宫内膜厚度与治疗前比较,差异有统计学意义(P<0.05)。观察组治疗后月经量、子宫内膜厚度低于对照组,经期时间短于对照组,差异有统计学意义(P<0.05)。2组均无宫腔粘连或感染等并发症发生。观察组术后1年复发率低于对照组,差异有统计学意义(P<0.05)。结论宫腔镜下EP切除术后应用活血通脉汤可有效预防EP复发。

Objective To explore the effect of Huoxue Tongmai Tang on the patients undergoing hysteroscopic endometrial polypectomy(EP).Methods A total of 100 patients who underwent hysteroscopic EP in the hospital from January 2018 to January 2021 were selected,and divided into the observation group and the control group using random number table method,with 50 cases in each group.The control group received oral administration of desogestrel and ethinylestradiol tablets,while the observation group received oral administration of Huoxue Tongmai Tang.The positive rates of estrogen receptor(ER)and progesterone receptor(PR)in the endometrium of the two groups before and after treatment,as well as the menstrual volume,menstrual period,endometrial thickness,postoperative recurrence rate,and incidence of complications were compared.Results The positive rate of ER in the endometrium of the observation group after treatment was lower than that before treatment,and the positive rate of PR was higher than that before treatment,with statistical significance(P<0.05).The positive rates of ER and PR in the endometrium of the control group after treatment were not statistically significant compared with that before treatment(P>0.05).After treatment,the ER positive rate in the endometrium of the obervation groups was lower than that of the control group,and the PR positive rate was higher than that of the control group,with statistically significant difference(P<0.05).There were statistically significant differences in menstrual volume,menstrual period,and endometrial thickness after treatment and before treatment between the two groups(P<0.05).After treatment,the menstrual volume and endometrial thickness of the observation group were lower than those of the control group,and the menstrual period was shorter than that of the control group,with statistically significant differences(P<0.05).There were no complications such as intrauterine adhesions or infections in both groups.The one-year postoperative recurrence rate in the observation group was lower than that in the control group,and the difference was statistically significant(P<0.05).Conclusion The application of Huoxue Tongmai Tang after hysteroscopic EP can effectively prevent EP recurrence.