透明帽辅助内镜下聚桂醇硬化剂注射治疗Ⅱ~Ⅲ度内痔的疗效观察

Observation on the clinical efficacy of transparent cap-assisted endoscopic injection of lauromacrogol sclerosing agent in the treatment of internal hemorrhoids of gradeⅡ-Ⅲ

目的观察透明帽辅助内镜下聚桂醇硬化剂注射治疗Ⅱ~Ⅲ度内痔的疗效。方法回顾性分析2019年1月至2022年1月南京市中医院内镜中心门诊收治的244例Ⅱ~Ⅲ度症状性内痔患者的临床资料,根据手术方式的不同,分为观察组(n=122,采用透明帽辅助内镜下聚桂醇硬化剂注射治疗)和对照组(n=122,采用PPH治疗),记录并观察比较两组手术时间及住院时间、术后并发症发生情况、术后复发情况、临床疗效及满意度情况。结果观察组的手术时间及住院时间短于对照组(P<0.05),术后24 h内的肛缘水肿、发热、便血、尿潴留、肛门狭窄等并发症总发生率低于对照组(2.5%vs.41.8%,P<0.001),满意度高于对照组(96.7%vs.77.0%,P<0.001);两组复发率(观察组8.2%vs.对照组4.9%)及总有效率(观察组96.7%vs.对照组98.4%)比较差异无统计学意义(P>0.05)。结论透明帽辅助内镜下聚桂醇硬化剂注射治疗Ⅱ~Ⅲ度症状性内痔具有操作简便、恢复快、安全有效、可重复治疗等特点,具有临床推广应用的价值。

Objectives To observe the efficacy of transparent cap-assisted endoscopic injection of lauromacrogol sclerosing agent in the treatment of internal hemorrhoids of gradeⅡ-Ⅲ.Methods A retrospective analysis of clinical data of 244 patients with internal hemorrhoids of gradeⅡ-Ⅲadmitted to the endoscopy center of Nanjing Hospital of Traditional Chinese Medicine from January 2019 to January 2022.Patients were divided into an observation group(n=122,treated with transparent cap-assisted endoscopic injection of lauromacrogol sclerosing agent)and a control group(n=122,treated with PPH).Operation time,hospitalization time,postoperative complications,postoperative recurrence,clinical efficacy,and satisfaction of the two groups were recorded and compared.Results The operation time and hospitalization time in the observation group were shorter than those in the control group(P<0.05).The total incidence of complications such as anal edema,fever,bloody stool,urinary retention,and anal stenosis within 24 hours after operation in the observation group was lower than that in the control group(2.5%vs.41.8%,P<0.001),and satisfaction was higher than that in the control group(96.7%vs.77.0%,P<0.001);There was no significant difference in the recurrence rate(8.2%in the observation group vs.4.9%in the control group)and the total effective rate(96.7%in the observation group vs.98.4%in the control group)between the two groups(P>0.05).Conclusion Transparent cap-assisted endoscopic injection of lauromacrogol sclerosing agent for the treatment of internal hemorrhoids of gradeⅡ-Ⅲhas the characteristics of simple operation,rapid recovery,safety,efficacy,and repeatability,making it worthy of clinical application.