氨磺必利治疗难治性精神分裂症的临床研究

A Clinical Study on the Treatment of Refractory Schizophrenia with Amisulpiride

研究评估了氨磺必利在治疗难治性精神分裂症方面的疗效。选取了68例观察对象,采用随机、双盲、对照设计,将患者分为观察组(采用常规药物+氨磺必利治疗)和参照组(仅常规药物治疗),对比两组患者治疗效果。结果显示,观察组患者在加用氨磺必利后,其阳性症状和阴性症状均显著改善,且不良反应发生率较低,生活质量评分较高,两种治疗方式在治疗难治性精神分裂症方面的差异具有统计学意义(P<0.05)。研究发现,氨磺必利在治疗难治性精神分裂症方面具有较高的疗效和安全性,可显著改善患者症状,不良反应发生率较低。

The study evaluated the efficacy of amisulpiride in the treatment of refractory schizophrenia.68 observation subjects were selected and a randomized,double-blind,controlled design was used.The patients were divided into an observation group(treated with conventional drugs and sulfamethoxazole)and a reference group(treated with conventional drugs only),and the treatment effects of the two groups were compared.The results showed that the observation group of patients showed significant improvement in both positive and negative symptoms after the addition of sulfamethoxazole,with a lower incidence of adverse reactions and a higher quality of life score.The difference between the two treatment methods in treating refractory schizophrenia was statistically significant(P<0.05).Research has found that sulfamethoxazole has high efficacy and safety in the treatment of refractory schizophrenia,significantly improving patient symptoms with a lower incidence of adverse reactions.