基于波形反演和LTI算法实现布拉格峰定位

Localization of Bragg Peak based on waveform inversion and LTI algorithm

为了使质子布拉格峰在介质中的定位效果更精确,以便应用于临床肿瘤的定位与治疗,提出一种三维布拉格峰定位算法。算法以频域全波形反演算法和LTI算法为基础,实现布拉格峰的定位。文中选取了5个目标布拉格峰位置,然后分别以这5个坐标位置为中心,在距离中心50mm内随机选取了10个初始布拉格峰位置,最终定位误差收敛在0.2mm~1.7mm,能够较好地满足质子治疗的定位精度要求。

In order to make the localization of proton Bragg peak in media more accurate,so as to be used in clinical tumor localization and treatment,a three-dimensional Bragg peak localization algorithm is proposed.The algorithm is based on frequency domain full waveform inversion algorithm and LTI algorithm to locate Bragg peak.In this paper,five target Bragg peak locations are selected,and then 10 initial Bragg peak locations are randomly selected within 50mm from the center with these 5 coordinates as the center.The final location error converges to 0.2mm~1.7mm,which can well meet the positioning accuracy requirements of proton therapy.