急性心肌梗死患者急诊PCI术后新发心房颤动状况及其影响因素

Status and Influencing Factors of New Onset Atrial Fibrillation in Patients with Acute Myocardial Infarction After Emergency PCI

目的探析急性心肌梗死(AMI)患者急诊经皮冠状动脉介入(PCI)术后新发心房颤动状况及其影响因素,以为后续防治提供科学依据。方法选取2020年8月至2021年8月义马煤业集团股份有限公司总医院收治的110例AMI患者,观察患者PCI术后新发心房颤动情况。调查患者一般资料和相关指标,探寻AMI患者PCI术后新发心房颤动及其影响因素。结果110例AMI患者PCI术后新发心房颤动的发生率为15.45%。发生组C反应蛋白(CRP)、白细胞介素(IL)-1β、脑钠肽(BNP)、尿酸、和肽素水平及合并糖尿病占比均高于未发生组,差异有统计学意义(P<0.05)。多因素logistic回归分析结果显示,CRP、IL-1β、BNP、尿酸、和肽素水平及合并糖尿病均为AMI患者PCI术后新发心房颤动的影响因素(P<0.05)。结论CRP、IL-1β、BNP、尿酸、和肽素水平及合并糖尿病均为AMI患者PCI术后新发心房颤动的独立影响因素,应加强上述影响因素的防控及早期采取相关干预,以减少新发心房颤动风险。

Objective To explore the status and influencing factors of new onset atrial fibrillation in patients with acute myocardial infarction(AMI)after emergency percutaneous coronary intervention(PCI),in order to provide scientific basis for subsequent prevention and treatment.Methods A total of 110 AMI patients admitted to the General Hospital of Yima Coal Industry Group Co.,Ltd.from August 2020 to August 2021 were selected to observe the incidence of new atrial fibrillation after PCI surgery.General information and related indicators of patients were investigated to explore new atrial fibrillation after PCI in AMI patients and its influencing factors.Results The incidence of new atrial fibrillation after PCI in 110 AMI patients was 15.45%.The levels of C-reactive protein(CRP),interleukin(IL)-1β,brain natriuretic peptide(BNP),uric acid,and copeptin of patients with diabetes in the occurrence group were higher than those in the non occurrence group,with a statistical significant difference(P<0.05).Multivariate logistic regression analysis showed that CRP,IL-1β,BNP,uric acid,copeptin levels and diabetes mellitus were all influencing factors for new onset atrial fibrillation after PCI in AMI patients(P<0.05).Conclusion CRP,IL-1β,BNP,uric acid,copeptin levels and diabetes are independent influencing factors of new onset atrial fibrillation in AMI patients after PCI.The prevention and control of these influencing factors should be strengthened and early intervention should be taken to reduce the risk of new onset atrial fibrillation.