中老年人心血管代谢性共病患病率与影响因素的Meta分析

Meta-analysis of the prevalence and influencing factors of cardiovascular metabolic comorbidity in middle-aged and elderly

目的评估中老年人心血管代谢性共病的患病率及影响因素。方法计算机检索中国知网、万方数据库、维普网、CBM、PubMed、Cochrane library、Embase、Scopus数据库,检索心血管代谢性共病患病率相关的文献,检索时间从建库起至今,由2名研究者独立完成文献纳入、数据提取、质量评价,再通过Stata17.0软件进行分析。结果本研究最终纳入14篇文献,共计332932例参与者。Meta分析的结果显示,中老年人心血管代谢性共病的患病率为14.6%(95%CI 10.0~19.2),女性、老年人、城市、经济状况较好、超重或肥胖、抑郁人群发生心血管代谢性共病的风险更高。结论中老年人心血管代谢性共病患病率较高,应在高风险人群中做好预防和管理的工作,应为弱势群体倾斜社会资源,提高整体健康水平。

Objective To evaluate the prevalence and influencing factors of cardiovascular metabolic comorbidity in middle-aged and elderly people.Methods We searched the CNKI,WanFang,VIP,CBM,PubMed,Cochrane library,Embase,Scopus databases to retrieve the literature related to the prevalence of cardiovascular metabolic comorbidity.The retrieval time was from the establishment of the database to the present.Two researchers independently completed the literature inclusion,data extraction,quality evaluation,and then analyzed by Stata17.0.Results A total of 14 studies involving 332,932 participants were included.The results of Meta-analysis showed that the prevalence of cardiovascular metabolic comorbidity in middle-aged and elderly people was 14.6%(95%CI 10.0~19.2),and the risk of cardiovascular metabolic comorbidity was higher in women,elderly people,urban people,people with better economic status,overweight or obesity,and people with depression.Conclusion The prevalence of cardiovascular metabolic comorbidity in middle-aged and elderly people is high.Researchers can do a good job in prevention and management of high-risk groups.Policy makers can tilt social resources for vulnerable groups and improve the overall health level.