吸食依托咪酯相关死亡1例的法医学鉴定和启示

Forensic Identifi cation and Inspiration of One Case of Etomidate Related Death

依托咪酯是一种用于诱导麻醉的催眠剂,具有起效快、维持时间短和循环稳定等特点,广泛运用于老年人以及并发心血管疾病患者和危重症患者的麻醉诱导。国家禁毒委发布的《2021年中国毒情形势报告》指出在部分地区存在滥用“烟粉”的情况,并将其主要成分依托咪酯定为毒品替代物质。但国内尚未见与依托咪酯相关死亡的案例报道。本文报道了一例未成年人在吸食依托咪酯后,因支气管肺炎加重致呼吸功能衰竭而死亡的案例,供同行借鉴参考。法医学实践中需要提高对依托咪酯不良反应及依托咪酯滥用的重视。

Etomidate is a hypnotic agent used for induction of anesthesia,characterized by rapid onset,short duration,and hemodynamic stability.It is widely used for anesthesia induction in elderly patients and those with cardiovascular disease and critical illness.The“2021 China Drug Situation Report”issued by the National Narcotics Control Commission pointed out that there is a situation of abuse of“smoke powder”in some areas,and its main component,etomidate,is identified as a drug substitute.However,there have been no reports of etomidate-related deaths in China.This article reports a case of a minor who died from respiratory failure due to exacerbation of bronchopneumonia after inhaling etomidate,for reference by peers.In forensic practice,attention should be paid to the adverse reactions of etomidate and the abuse of etomidate.