摘要
恶性肠梗阻是晚期肿瘤患者常见终末期事件,20%的肿瘤最终发展为恶性肠梗阻。然而,恶性肠梗阻患者预后差,缺乏有效的治疗方法,恶性肠梗阻的诊疗路径、治疗策略、手术适应证和禁忌证、手术治疗能否获益等均是需要探索性的课题。中国抗癌协会组织多位在恶性肠梗阻诊疗领域具有丰富临床经验的专家就恶性肠梗阻的定义、流行病学、病理生理、治疗原则和方法、疗效评价进行讨论,重新定义恶性肠梗阻,总结恶性肠梗阻发生、发展的病理生理机制,提出恶性肠梗阻“多学科会诊、分级诊疗、整合治疗和精准强化”治疗策略,明确手术适应证、手术方式、手术效果评价方法和指标,并对恶性肠梗阻手术治疗与药物治疗效果进行了评价。《恶性肠梗阻治疗中国专家共识(2023年)》对提高恶性肠梗阻规范化治疗水平具有一定意义。
Malignant bowel obstruction is a common end-stage event in advanced cancer patients,and 20%of tumors eventually develop into malignant bow-el obstruction.However,malignant bowel obstruction patients have poor prognosis and lack of effective treatment.The diagnosis and treatment path,treatment strategy,surgical indications and contraindications,and the benefit of surgical treatments are all topics that need to be explored.The Chinese Anti-Cancer Association organized many experts with rich clinical experience in the field of diagnosis and treatment of malignant bow-el obstruction to discuss the definition,epidemiology,pathophysiology,treatment principles and methods,and efficacy evaluation of malignant bowel obstruction,redefined the definition of malignant bowel obstruction,and summarized the pathophysiological mechanism of the occurrence and development of malignant bowel obstruction.The treatment strategy of"multi-disciplinary consultation,hierarchical diagnosis and treatment,integrated treatment and precise intensification"for malignant bowel obstruction were proposed,and the indications,contraindications,surgical methods and evaluation methods and indicators of the surgical effect of malignant bowel obstruction were defined,and the effects of surgical treatment and drug therapy for malignant bowel obstruction were evaluated.The Chinese expert consensus on the treatment of malignant bowel obstruction(2023)will certain significance for improving the standard treatment level of malignant bowel obstruction.
出处
《肿瘤代谢与营养电子杂志》
2023年第6期730-737,共8页
Electronic Journal of Metabolism and Nutrition of Cancer
基金
国家重点研发计划项目(2022YFC2009601)。
关键词
恶性肠梗阻
诊断
治疗
专家共识
Malignant bowel obstruction
Diagnosis
Treatment
Expert consensus