以眼科首诊的朗格汉斯细胞组织细胞增生症一例

A case of Langerhans cell histiocytosis first diagnosed in ophthalmology

患者,男性,1岁9个月。以“发现右眼上、下眼睑肿物25 d”首诊于眼科,要求切除,但经影像学及病理学检查,诊断为多发性朗格汉斯细胞组织细胞增生症,且全身骨骼多处出现溶骨性改变,不符合切除指征。给予多次全身化学治疗后眼部肿物明显变小。该例诊治提醒眼科医生,眼部肿物可由全身系统性疾病引起,不可盲目切除,必要时做进一步检查。术中切除物均建议行病理活组织检查,以免延误治疗。

patient,male,1year and 9months old,was first diagnosed as“eye tumor”in the ophthalmology department and requested for excision.But it was diagnosed as multiple Langerhans cell histiocytosis(LCH)through imaging and pathological examination ultimately.Bone lytic changes appeared in many parts of the whole body,which did not meet the indication of excision.The tumor was smaller after systemic chemotherapy.The diagnosis and treatment of this case suggests ophthalmologists that eye tumors can be caused by caused by systemic diseases,systemic diseases.During operation,it is recommended to perform pathological biopsy to avoid treatment delay.