摘要
氢气在能源领域的优势已日渐凸显,其在医学领域同样是一种清洁、高效、经济的治疗手段。氢医学领域主要包括氢气对疾病的基础研究和临床研究,如氢气的使用方法、剂量、对健康的促进作用、对疾病的治疗效果以及作用机理等。氢分子可以清除羟基自由基和过氧亚硝酸盐,对氧化应激和炎症相关疾病具有显著的治疗效果,同时其作为一种内源性气体,无毒无害,对人体不会造成不良反应。通过直接摄入和控制释放等方式,可以实现对脑和神经系统疾病、心血管疾病、糖尿病和癌症等疾病的靶向治疗。介绍了释放氢气的不同方式及其在医学领域的研究进展,并对氢医学的科学和实践问题进行了展望,以期为氢气在生物医学领域的应用研究提供参考。
Hydrogen has attracted a lot of attention in energy field,at the same time,it is also a clean,efficient and economical technology in medical field.The field of hydrogen medicine mainly includes basic and clinical research on the effects of hydro⁃gen on diseases,such as the usage methods,dosage,health promoting effects,therapeutic effects on diseases,and mechanisms of action of hydrogen.Hydrogen can remove hydroxyl radicals and peroxynitrites,which have significant therapeutic effect for oxi⁃dative stress and inflammation related diseases.At the same time,as an endogenous gas,it is non-toxic and harmless,and will not cause adverse reactions to human body.Targeted treatment of brain and nervous system diseases,cardiovascular diseases,di⁃abetes,cancer and other diseases can be achieved through direct intake and controlled release.The article introduced the differ⁃ent ways of releasing hydrogen gas and its applications in the medical field,and looked forward to the scientific and practical is⁃sues of hydrogen medicine,in order to provide reference for the application research of hydrogen in the biomedical field.
作者
刘星宇
赵国利
李雪婧
LIU Xingyu;ZHAO Guoli;LI Xuejing(SINOPEC(Dalian)Research Institute of Petroleum and Petrochemical Co.Ltd.,Liaoning Dalian 116045,China)
出处
《生物技术进展》
2024年第1期102-110,共9页
Current Biotechnology
基金
国家重点研发项目(2022YFF0705100)。
关键词
氢气
纳米材料
抗氧化
抗炎
hydrogen
nanoparticles
antioxidant
anti-inflammatory