腹横纹微小切口手术治疗小儿腹股沟疝的效果及对炎性因子的影响

Effect of abdominal transverse microincision surgery on inguinal hernia in children and its influence on inflammatory factors

目的:探讨腹横纹微切口手术治疗小儿腹股沟疝的效果及对炎性因子的影响。方法:选取2020年6月至2022年6月于我院接受治疗的106例腹股沟疝患儿作为研究对象,按照随机数字表法分为对照组和观察组,各53例。对照组接受传统手术治疗,观察组接受腹横纹微切口手术治疗。对比两组围术期相关指标(手术时间、切口长度、住院时间),对比术前及术后1 d炎症因子指标水平及肠粘膜功能相关指标水平,记录术后并发症发生情况。结果:观察组切口长度、手术及住院时间均明显短于对照组(P<0.05)。治疗前,两组白细胞介素-6(Interleukin-6,IL-6)、肿瘤坏死因子-α(Tumor necrosis factor-α,TNF-α)及超敏C反应蛋白(Hypersensitive C-reactive protein,hs-CRP)水平无明显差异(P>0.05);治疗后,两组IL-6、TNF-α及hs-CRP均明显升高,但观察组IL-6、TNF-α及hs-CRP水平均明显低于对照组(P<0.05)。对照组术后的D-乳酸(D-lactic acid,D-LA)、尿肠形脂肪酸结合蛋白(Intestinal-fatty acid binding protein,i-FABP)及尿乳果糖/甘露醇(Lactulose/Mannitol,L/M)比值水平均明显升高(P<0.05);观察组术后D-LA、尿i-FABP及尿L/M水平与术前无明显差异(P>0.05),均明显低于对照组(P<0.05)。观察组并发症发生率明显低于对照组(P<0.05)。结论:腹横纹微切口手术应用于小儿腹股沟疝的治疗中效果较佳,可缩短术后患者的恢复时间,减轻炎症因子的影响,且安全性较高。

Objective:To investigate the effect of abdominal transverse micro incision surgery on inguinal hernia in children and its influence on inflammatory factors.Methods:A total of 106 children with inguinal hernia in our hospital from June 2020 to June 2022 were selected as research subjects and were divided into control group and observation group,according to random number table method,with 53 cases in each group.Children in the control group were given traditional surgical treatment,while children in the observation group were given abdominal transverse micro incision surgery.The perioperative related indicators(surgical time,incision length,hospital stay),inflammatory factor indicators and relevant indicators of intestinal mucosal function before and 1 day after surgery Intestinal-fatty acid binding protein(i-FABP),Lactulose/Mannitol(L/M),D-lactic acid(D-LA)were compared.At the same time,the occurrence of postoperative complications between two groups were recorded.Results:The incision length in the observation group was shorter than that in the control group,and the operation and hospitalization time were shorter than those in the control group,with significant differences(P<0.05).There were no differences in the levels of interleukin-6(IL-6),tumor necrosis factor-α(TNF-α),hypersensitive C-reactive protein(hs-CRP)before treatment in both groups(P>0.05);after treatment,IL-6 and TNF-αand hs-CRP were increased in both groups,but IL-6,TNF-αand hs-CRP in the observation group were lower than those in the control group(P<0.05).The postoperative D-lactic acid(D-LA),intestinal-fatty acid binding protein(i-FABP),lactulose/mannitol(L/M)in the control group were higher than those before surgery(P<0.05);The postoperative D-LA,i-FABP and L/M levels in the observation group were not different compared to preoperative(P>0.05),and were lower than those in the control group(P<0.05).The incidence of complications in the observation group was lower than that in the control group,with significant difference(P<0.05).Conclusion:The abdominal transverse microincision surgery in the treatment of inguinal hernia in children has a better effect,can shorten the recovery time,reduce the impact of inflammatory factors,and has a high safety.