益骨舒筋通络汤结合核心稳定性锻炼治疗膝骨关节炎临床研究

Clinical Study on the Treatment of Knee Osteoarthritis withBone-Replenishing and Tendon-Stretching and Collateral-DredgingDecoction Combined with Core Stability Exercise

目的:观察益骨舒筋通络汤结合核心稳定性锻炼治疗膝骨关节炎的临床疗效。方法:选取2020年5月到2022年5月项城市卫校中西医结合医院治疗的膝骨关节炎患者98例,按照随机数字表法分为对照组和观察组,每组49例。对照组给予核心稳定性锻炼干预,观察组在对照组治疗的基础上加用益骨舒筋通络汤治疗。观察两组膝骨关节炎症状评分、疼痛评分、生活质量评分、平衡能力、下肢肌力、炎症因子水平(白细胞介素-6、白细胞介素-10、肿瘤坏死因子)变化情况及临床疗效。结果:观察组有效率为97.96%,对照组有效率为81.63%,观察组有效率高于对照组,差异有统计学意义(P<0.05);观察组治疗后晨僵评分、生活难度评分、疼痛难度评分低于对照组,差异有统计学意义(P<0.05);观察组治疗后闭目原地踏步时间、闭眼单脚站立时间、30 s坐-站测试次数高于对照组,差异有统计学意义(P<0.05);观察组治疗后白细胞介素-6、白细胞介素-10、肿瘤坏死因子水平低于对照组,差异有统计学意义(P<0.05);观察组治疗后疼痛评分低于对照组,生活质量评分高于对照组,差异有统计学意义(P<0.05)。结论:益骨舒筋通络汤结合核心稳定性锻炼治疗膝骨关节炎能够改善患者膝骨关节炎症状,减轻疼痛,提高患者生活质量、平衡能力及下肢肌力,降低炎症因子水平。

Objective:To observe the clinical efficacy of Bone-Replenishing and Tendon-Stretching and Collateral-Dredging Decoction combined with core stability exercise on knee osteoarthritis.Methods:A total of 98 patients with knee osteoarthritis treated in Xiangcheng Health School Integrated Traditional and Western Medicine Hospital from May 2020 to May 2022 were selected and divided into the control group and the observation group according to the random number table method,with 49 cases in each group.The control group was given core stability exercise intervention,while the observation group was treated with Bone-Replenishing and Tendon-Stretc-hing and Collateral-Dredging Decoction on the basis of the treatment of the control group.The changes in knee osteoarthritis symptom score,pain score,quality of life score,balance ability,lower limb muscle strength,inflammatory factor levels(including interleukin-6,interleukin-10,tumor necrosis factor)and clinical efficacy of the two groups were observed.Results:The effective rate of the observation group was 97.96%,while that of the control group was 81.63%.The effective rate of the observation group was higher than that of the control group,and the difference was statistically significant(P<0.05).After treatment,the morning stiffness score,difficulty in life score and pain difficulty score of the observation group were lower than those of the control group,and all the differences were statistical-ly significant(P<0.05);The time of stepping in place with eyes closed,the time of standing on one foot with eyes closed,and the times of 30-second sit-stand test in the observation group were higher than those in the control group,and all the differences were statis-tically significant(P<0.05);The levels of interleukin-6,interleukin-10,and tumor necrosis factor in the observation group were lower than those in the control group,all the differences were statistically significant(P<0.05);The pain score in the observation group was lower than that in the control group,while the quality of life score was higher than that in the control group,and all the differences were statistically significant(P<0.05).Conclusion:Bone-Replenishing and Tendon-Stretching and Collateral-Dredging Decoction combined with core stability exercise can improve the symptoms of knee osteoarthritis,relieve pain,improve the quality of life,balance ability and lower limb muscle strength of patients,and reduce the level of inflammatory factors.