胸腔镜手术治疗肺癌的临床效果分析

Analysis of Clinical Effect of Thoracoscopic Surgery in Treatment of Lung Cancer

目的:观察胸腔镜手术治疗肺癌的临床效果。方法:选取2017年1月—2022年7月吉首市湘西自治州肿瘤医院收治的70例肺癌患者作为研究对象,采用随机数字表法分为两组,各35例。对照组实施开胸手术治疗,观察组实施胸腔镜手术治疗,比较两组临床疗效。结果:观察组总有效率高于对照组,差异有统计学意义(P=0.012)。术后,两组生长激素、皮质醇、前列腺素水平高于治疗前,但观察组低于对照组,两组全血凝固时间水平低于治疗前,但观察组高于对照组,差异有统计学意义(P<0.05)。术后,两组白细胞介素-6、C反应蛋白、肿瘤坏死因子-α水平高于术前,但观察组低于对照组,差异有统计学意义(P<0.05)。观察组术中出血量、术后引流量、淋巴清扫数少于对照组,住院时间短于对照组,差异有统计学意义(P<0.05)。结论:胸腔镜手术治疗肺癌的临床效果显著,可降低患者应激以及炎性指标,改善手术指标,缩短住院时间。

Objective:To observe the clinical effect of thoracoscopic surgery in treatment of lung cancer.Methods:A total of 70 patients with lung cancer admitted to the Cancer Hospital of Xiangxi Autonomous Prefecture in Jishou City from January 2017 to July 2022 were selected as the study subjects.They were divided into two groups according to random number table method,with 35 cases in each group.The control group was treated with open chest surgery,and the observation group was treated with thoracoscopic surgery.Clinical efficacy was compared between two groups.Results:The total effective rate in the observation group was higher than that in the control group,and the difference was statistically significant(P=0.012).After surgery,the levels of growth hormone,cortisol and prostaglandin in the two groups were higher than those before treatment,but the levels in the observation group were lower than those in the control group,and the levels of whole blood coagulation time in the two groups were lower than those before treatment,but the levels in the observation group were higher than those in the control group,and the difference was statistically significant(P<0.05).After surgery,the levels of interleukin-6,C-reactive protein and tumor necrosis factor-αin the two groups were higher than those before surgery,but the levels in the observation group were lower than those in the control group,and the difference was statistically significant(P<0.05).The intraoperative blood loss,postoperative drainage volume and number of lymphatic node dissection in the observation group were lower than those in the control group,and the length of hospital stay in the observation group was shorter than that in the control group,and the difference was statistically significant(P<0.05).Conclusion:Thoracoscopic surgery has a significant clinical effect in treatment of lung cancer,and can reduce stress and inflammation indicators,improve the treatment indicators,and shorten the length of hospital stay.