单中心333例直立倾斜试验数据分析

Analysis of 333 cases of head-up tilt test from a single center

目的 探讨直立倾斜试验中年龄、性别与阳性结果以及阳性相关指标之间的关系。方法 对以晕厥查因进行直立倾斜试验的所有患者共计333例进行回顾性分析,其中男152例(45.6%),女181例(54.4%)。阳性患者分为基础试验阳性组以及药物试验阳性组。阳性分型为血管抑制型、心脏抑制型、混合型;按照年龄分为13~35岁、36~50岁、51~65岁、>65岁。结果 不同年龄组别间(从小到大)女性阳性患者数差异有统计学意义(P<0.05),具体表现为年龄越小,女性阳性人数越多;阳性中混合型患者在不同年龄组间,表现为年龄越大,混合型患者越少,差异有统计学意义(P<0.05);混合型患者在性别组间差异有统计学意义(P<0.05),表现为女性患者明显多于男性;基础试验以及药物试验阳性患者中,随着年龄的增加,基础试验开始时的血压与出现阳性结果时的血压差值呈现极度相关性(P<0.001),即年龄越大,阳性时血压下降越明显。结论 结合性别、年龄的不同,直立倾斜试验的阳性率、阳性分型、结束时的血压下降水平均存在差异。

Objective To explore the relationship between age,gender and positive results and positive correlation index in head-up tilt test(HUTT).Methods A retrospective review of all the 333 patients who have underwent HUTT test for syncope diagnosis were conducted,included 152 males(45.6%)and 181 females(54.4%).The positive patients has been divided into the basic experiment positive group and the drug test positive group.The positive results were divided into vasodepressive type,cardioinhibitory type and mixture type.All patients were divided into 13-35 years,36-50 years,51-65 years and older than 65 years groups according to their age.Results Among different age groups(from young to old),the number of female positive patients had statistical difference,specifically,the younger the age,the more female positive patients.Positive mixture type patients in different age groups,the older the age,the less mixture type patients and the difference was statistically significant(P<0.05).There was significant difference between gender groups in mixture type patients,with female patients significantly more than male patients(P<0.05).In the the basic experiment positive group and the drug test positive group,the difference between blood pressure at the beginning of baseline trial and blood pressure at the time of positive results showed an extreme correlation with increasing age(P<0.001).In other words,the older the age,the more significant the decrease in blood pressure at positive results.Conclusion Considering the difference of gender and age,there were statistical differences in positive rate,positive typing,and blood pressure drop at the end of HUTT.