阿托伐他汀钙片联合抗骨质疏松药物治疗对脑卒中偏瘫患者下肢功能影响分析

Effect analysis of atorvastatin calcium tablets combined with anti-osteoporosis drugs on lower limb function in stroke patients with hemiplegia

目的 探究阿托伐他汀钙片联合抗骨质疏松药物治疗对脑卒中偏瘫患者下肢功能的影响。方法 68例脑卒中偏瘫患者,采用随机数字表法分为对照组和观察组,每组34例。对照组给予抗骨质疏松药物治疗,观察组在对照组用药基础上给予阿托伐他汀钙片治疗。比较两组患者治疗前后的日常生活活动能力评估量表(ADL)、美国国立卫生研究院卒中量表(NIHSS)、Berg平衡量表(BBS)、FuglMeyer运动功能评定量表(FMA)、功能综合评定量表(FCA)、下肢肌力、下肢Brunnstrom分期评分。结果 治疗后,观察组患者的ADL评分(85.56±9.42)分、BBS评分(42.41±3.19)分、FMA评分(80.36±4.79)分、FCA评分(85.33±5.15)分均高于对照组的(70.39±6.73)、(34.77±4.64)、(71.25±5.80)、(71.41±6.52)分, NIHSS评分(8.61±1.43)分低于对照组的(14.74±3.09)分(P<0.05)。治疗后,观察组患者下肢肌力评分(4.90±1.01)分、下肢Brunnstrom分期评分(4.49±1.29)分均高于对照组的(3.49±1.27)、(3.61±1.59)分(P<0.05)。结论 给予脑卒中偏瘫患者阿托伐他汀钙片联合抗骨质疏松药物进行治疗,可显著改善患者的相关指标评分,对减轻病症影响具有重要作用,下肢功能恢复效果显著,值得广泛推广。

Objective To explore the effect of atorvastatin calcium tablets combined with antiosteoporosis drugs on lower limb function in stroke patients with hemiplegia.Methods 68 stroke patients with hemiplegia were divided into a control group and an observation group by random number table method,with 34 cases in each group.The control group was treated with anti-osteoporosis drugs,and the observation group was treated with atorvastatin calcium tablets on the basis of the control group.Both groups were compared in terms of scores of Activities of Daily Living(ADL),National Institutes of Health Stroke Scale(NIHSS),Berg Balance Scale(BBS),Fugl-Meyer Assessment scale(FMA),Functional Comprehensive Assessment Scale(FCA),lower-limb muscle strength and lower-limb Brunnstrom staging score before and after treatment.Results After treatment,the observation group had ADL score of(85.56±9.42)points,BBS score of(42.41±3.19)points,FMA score of(80.36±4.79)points and FCA score of(85.33±5.15)points,which were higher than those of(70.39±6.73),(34.77±4.64),(71.25±5.80)and(71.41±6.52)points in the control group,and the NIHSS score of(8.61±1.43)points in the observation group was lower than(14.74±3.09)points in the control group(P<0.05).After treatment,the lower-limb muscle strength score of(4.90±1.01)points and lower-limb Brunnstrom staging score of(4.49±1.29)points in the observation group were higher than those of(3.49±1.27)and(3.61±1.59)points in the control group(P<0.05).Conclusion Atorvastatin calcium tablets combined with anti-osteoporosis drugs can significantly improve the relevant index scores of patients with post-stroke hemiplegia,which plays an important role in reducing the impact of the disease,and has a significant effect on the recovery of lower limb function,which is worthy of widespread promotion.