冠状动脉钙化与乳腺癌患者放疗后心血管疾病相关性

Correlation analysis between coronary artery calcifications and cardiovascular disease in patients with breast cancer after radiotherapy

冠状动脉钙化(CAC)是一个独立的心血管疾病(CVD)危险因素,研究发现可通过乳腺癌患者放射治疗计划CT扫描,自动量化CAC,从而提前识别出放疗后CVD风险增高的患者并采取干预。本文综述了目前研究CAC与乳腺癌患者放疗后心脏不良反应相关性的文献,以期为临床提供降低乳腺癌患者放疗后CVD风险的策略。

Coronary artery calcifications(CAC)is an independent risk factor for cardiovascular disease(CVD).It has been revealed that this condition can be automatically quantified through computerize tomographic(CT)scan contained in radiotherapy plan for patients with breast cancer,with which,physicians can identify the patients with increased risk of CVD after radiotherapy prematurely and take intervention measures in advance.In this article,the current literature and research progress on the correlation between CAC and cardiotoxicity in patients with breast cancer after radiotherapy were reviewed,expecting to provide a strategy to reduce the CVD risk in patients with breast cancer after radiotherapy.