摘要
针刺干预卒中后抑郁(PSD)主要涉及cAMP信号通路、MAPK信号通路、PI3K/Akt/mTOR信号通路、NF-κB信号通路、CREB信号通路,CaMK信号通路。这些信号通路之间形成了多样的调控网络,起到减轻炎症反应,抑制细胞凋亡,提高神经可塑性,促进血管新生,保护神经元等关键作用。
The signaling pathways involved in acupuncture intervention in post-stroke depression(PSD)mainly include cAMP signaling pathway,MAPK signaling pathway,PI3K/Akt/mTOR signaling pathway,NF-kB signaling pathway,CREB signaling pathway,and CaMK signaling pathway.A variety of regulatory networks are formed between these signaling pathways,which play a key role in reducing inflammation,inhibiting apoptosis,improving neuroplasticity,promoting angiogenesis,and protecting neurons.
作者
戴泽旭
何凯峰
黄杰杰
韩文婷
王丽芬
Dai Zexu;He Kaifeng;Huang Jiejie;Han Wenting;Wang Lifen(Master Degree Student of Grade 2021,Shaanxi University of Chinese Medicine,Xianyang 712046,China;Department of Acupuncture and Moxibustion,Shaanxi Hospital of Traditional Chinese Medicine,Xian 710000,China)
出处
《国际中医中药杂志》
2024年第1期129-133,共5页
International Journal of Traditional Chinese Medicine
基金
陕西省自然科学基础研究计划项目(2021JM-578)。
关键词
针刺
中风
抑郁症
信号通路
综述
Acupuncture
Stroke
Depression
Signaling pathway
Review
