客观测量身体行为的大型人群队列研究进展与实践

Progress and practice of objective measurement of physical behaviors in large-scale cohort research

受限于传统自我报告问卷测量方法的信、效度,身体行为(身体活动、久坐行为和睡眠)的准确测量受到很大限制。随着科学技术的发展,加速度计等客观测量设备能够更加准确、全面地测量身体行为相关特征,并逐渐为大规模流行病学研究所用。然而,我国乃至亚洲人群尚缺乏采集身体行为客观测量数据的大型队列研究。中国慢性病前瞻性研究(CKB)项目在第三次重复调查(2020年8月至2021年12月)使用Axivity AX3腕式三轴加速度计测量研究对象的日常活动及睡眠情况,最终共纳入全国10个项目地区20370名研究对象,其中女性占65.2%,年龄(65.4±9.1)岁,不同项目地区研究对象的身体行为活动水平具有较大差异。CKB项目开展的身体行为客观测量数据为描述我国中老年人24 h身体行为特征、探究身体活动、久坐行为、睡眠的健康效应以及其与疾病的深入研究提供了具有重要价值的科研资源。

Due to the limited reliability of traditional self-completed questionnaire,the accuracy of measurement of physical behaviors(physical activity,sedentary behavior and sleep)is not high.With the development of technology,wearable devices(e.g.accelerometer)can be used for more accurate measurement of physical behaviors and have great application potential in large-scale research.However,the data of objective measurement of physical behaviors from large-scale cohort research in Asian populations is still limited.Between August 2020 and December 2021,the 3rd resurvey of China Kadoorie Biobank(CKB)project used Axivity AX3 wrist triaxial accelerometer to collect the data of participants'daily activity and sleep status.A total of 20370 participants from 10 study areas were included in the study,in whom 65.2%were women,and the age was(65.4±9.1)years.The participants'physical activity level varied greatly in different study areas.The objective measurement of participants'physical behaviors in CKB project has provided valuable resources for the description of 24-hour patterns of physical behaviors and evaluation of the health effect of physical activity,sedentary behavior and sleep as well as their association with diseases in the elderly in China.