激光诱导击穿光谱技术在生物医学中的研究进展

Research Progress on Laser-Induced Breakdown Spectroscopyin Biomedicine

生物体内元素的微小变化可以直接影响生物的代谢和生理过程。快速、精准的生物体内元素定性定量分析,是新陈代谢检测以及临床疾病诊断中不可或缺的部分。随着医学检测技术的不断发展和临床需求的不断增加,寻找一种更新、更快、适应性更强的临床分析和诊断技术成为当前的研究热点。在生物医学研究中,激光诱导击穿光谱(LIBS)技术凭借着快速、实时、多元素同步检测的优势,在血液、病理组织检测和元素分布成像等方面展现出了极大的应用价值。本综述回顾了近年来LIBS技术在生物医学应用中的研究状况和最新进展,基于目前的研究状况,评估了LIBS技术在血液检测、生物组织分析、元素成像应用领域的挑战和机遇,还为进一步促进LIBS技术在生物医学领域的应用提供了建议。

Minor changes to elements in organisms can have a direct impact on their metabolism and physiological processes.Rapid and accurate qualitative and quantitative analyses of these elements are critical for both metabolism detection and clinical disease diagnosis.As medical detection technology continues to develop and clinical demand continues to increase,researchers are seeking newer,faster,and more adaptable clinical analysis and diagnostic technologies.Because of its fast,real-time,and multi-element simultaneous detection capabilities,laser-induced breakdown spectroscopy(LIBS)technology has shown great promise in recent years for use in blood and pathological tissue detection and elemental distribution imaging.This paper provides a comprehensive review of the current research status and latest progress of LIBS technology in biomedical applications and evaluates the challenges and opportunities of LIBS technology in the application fields of blood detection,biological tissue analysis,and elemental imaging.The paper also provides suggestions for further promoting the application of LIBS technology in the biomedical field.