某院门诊患儿雾化吸入用药合理性分析

Rationality of Aerosol Inhalation Medication in Pediatric Outpatient

目的:调查郑州大学第三附属医院门诊患儿雾化吸入用药现状,分析评价其合理性,为临床合理用药提供参考。方法:采用回顾性分析法,从医院信息系统提取2022年1-3月门诊患儿应用雾化药物处方1017张,对患儿性别、年龄、临床诊断、雾化剂品种、使用量及联合用药情况等进行统计分析,评价该院儿科雾化吸入用药的合理性。结果:1017张雾化用药处方中,单独用药20.16%,二联用药56.05%,三联用药23.78%。在所有种类雾化药物中,糖皮质激素应用最广泛,使用率87.61%。雾化药与口服药联用处方占28.52%。雾化药物主要应用于呼吸道感染、支气管炎、肺炎、哮喘、喉炎等22类临床诊断。不合理处方占3.15%,主要为适应证不适宜和遴选药品不适宜。结论:我院门诊患儿雾化吸入联合用药普遍存在,用药符合治疗指南。药品拓展性应用有循证医学证据支持,使用合理,但亦存在部分不合理用药情况,需进一步规范。

Objective:To investigate the current status of aerosol inhalation medication in the pediatric outpatient of the Third Affiliated Hospital of Zhengzhou University,to analyze and evaluate its rationality,so as to provide reference for clinical rational drug use.Methods:Retrospective analysis was conducted by extracting data from the hospital information system on 1,017 prescriptions for aerosol inhalation medication in pediatric outpatient from Jan.to Mar.2022.Statistical analysis was performed on gender,age,clinical diagnosis,types of nebulizers,dosage,and drug combination to evaluate the rationality of aerosol inhalation medication in pediatric outpatient.Results:Among the 1,017 prescriptions for aerosol inhalation medication,20.16%were for single drug,56.05%for dual medication,and 23.78%for triple medication.Glucocorticoids were the most widely used among all aerosol inhalation medication,with a utilization rate of 87.61%.Prescriptions with aerosol and oral medications accounted for 28.52%.Aerosol inhalation medication was primarily used for 22 clinical diagnoses,including respiratory infections,bronchitis,pneumonia,asthma and laryngitis.The proportion of irrational prescriptions was 3.15%,mainly for inappropriate indications and unsuitable drug selection.Conclusion:Combination therapy with aerosol inhalation is common in pediatric outpatient of our hospital,and medication usage generally aligns with treatment guidelines.The expanded use of drugs is supported by evidence-based medicine,demonstrating rationale utilization.However,there are instances of irrational drug use that need further standardization.