肝病治疗仪治疗代谢综合征合并非酒精性脂肪肝的疗效观察

Observation on the Therapeutic Effect of HD Liver Disease Treatment Instrument in the Treatment of Metabolic Syndrome Combined with Nonalcoholic Fatty Liver

目的观察HD肝病治疗仪治疗代谢综合征(metabolic syndrome,MetS)合并非酒精性脂肪肝(non-alcoholic fatty liver disease,NAFLD)的疗效。方法纳入2022年1月至2022年6月于辽宁中医药大学附属医院就诊的93例MetS合并NAFLD患者作为研究对象,随机分为对照组、用药组及治疗仪组各31例。所有患者均进行改善生活习惯等常规治疗。在此基础上用药组予水飞蓟宾胶囊70 mg日3次口服;治疗仪组予水飞蓟宾胶囊70 mg日3次口服、HD肝病治疗仪30 min日2次,每周5~7 d治疗。对照组治疗时间、用药组治疗时间、治疗仪组治疗时间均为连续4 w。对比各组治疗前后ALT、AST、GGT、TC、TG、HDL-C、FBG、PBG-2h、HbA1c、INS、HOMA-IR指数、UA的水平变化。结果各组治疗前肝功能、血脂、血糖、尿酸相关指标比较,P>0.05。各组治疗后各指标水平与治疗前相比均有降低,P<0.05。治疗后用药组及治疗仪组指标水平明显低于治疗后对照组P<0.05,治疗后治疗仪组血脂、血糖、尿酸指标水平低于用药组,P<0.05,治疗后治疗仪组肝功能指标水平低于用药组,P>0.05。对照组总有效率51.60%,共16例;用药组总有效率71.00%,共22例;治疗仪组总有效率90.32%,共2例痊愈病例,共26例有效病例;总有效率治疗仪组显著高于对照组及用药组,以P<0.05为差异具有统计学意义。结论MetS合并NAFLD对HD肝病治疗仪疗效反馈良好。

Objective To observe the efficacy of HD liver disease treatment instrument in the treatment of metabolic syndrome(MetS)combined with nonalcoholic fatty liver disease(NAFLD).Methods 93 patients with MetS combined with NAFLD who were treated at the Affiliated Hospital of Liaoning University of Traditional Chinese Medicine from January 2022 to June 2022 were included as the study subjects.They were randomly divided into a control group,a medication group,and a treatment instrument group,with 31 patients in each group.All patients received routine treatment such as improving their lifestyle habits.On this basis,the medication group was given 70 mg of silybin capsules orally three times a day;the treatment instrument group was given 70 mg of Silybin capsules orally three times a day,and the HD liver disease treatment instrument was used twice a day for 30 minutes,with treatment lasting 5~7 days per week.The treatment time of the control group,the medication group,and the treatment instrument group were all continuous for 4 weeks.The levels of ALT,AST,GGT,TC,TG,HDL-C,FBG,PBG-2h,HbA1c,INS,HOMA-IR index,and UA before and after treatment in each group were compared.Results The liver function,blood lipids,blood glucose,and uric acid related indicators among each group were compared before treatment(P>0.05).After treatment,the levels of various indicators in each group decreased compared to before treatment(P<0.05).After treatment,the levels of indicators in the medication group and the treatment instrument group were significantly lower than those in the control group(P<0.05).The levels of blood lipids,blood glucose,and uric acid indicators in the treatment instrument group were lower than those in the medication group(P<0.05).The levels of liver function indicators in the treatment instrument group were lower than those in the medication group(P>0.05).The total effective rate of the control group was 51.60%,with a total of 16 cases;the total effective rate of the medication group was 71.00%,with a total of 22 cases;the total effective rate of the treatment instrument group was 90.32%,with a total of 2 cured cases and 26 effective cases;the total effective rate of the treatment instrument group was significantly higher than that of the control group and the medication group,with a statistically significant difference(P<0.05).Conclusion The combination of MetS and NAFLD provides good feedback on the efficacy of HD liver disease treatment equipment.