因宫颈机能不全行孕期经阴道宫颈环扎术孕妇妊娠结局影响因素分析

Influencing factors of pregnancy outcomes of pregnant women with transvaginal cervical cerclage during pregnancy due to cervical insufficiency

目的:探讨因宫颈机能不全行孕期经阴道宫颈环扎术(TVC)的孕妇妊娠结局的影响因素。方法:选择2016年1月至2022年12月郑州大学第一附属医院收治的328例因宫颈机能不全行孕期TVC的孕妇,以分娩孕周≥28周且新生儿存活为成功标准,260例成功,68例失败。采用Logistic回归分析筛选TVC妊娠结局的影响因素。结果:Logistic回归分析结果显示,年龄、既往孕中期自然流产和(或)早产次数、辅助生殖助孕史、术后并发症是TVC孕妇妊娠结局的影响因素,OR(95%CI)分别为1.110(1.040~1.185)、1.519(1.027~2.248)、0.436(0.214~0.891)和4.711(1.544~14.372)。结论:年龄、既往孕中期自然流产和(或)早产次数、辅助生殖助孕史、术后并发症是单胎孕期TVC疗效的影响因素。

Aim:To investigate the influencing factors of pregnancy outcomes of pregnant women underwent transvaginal cervical cerclage(TVC)during pregnancy due to cervical insufficiency.Methods:From January 2016 to December 2022,a total of 328 singleton pregnant women who underwent TVC due to cervical insufficiency in the First Affiliated Hospital of Zhengzhou University were selected.According to the criteria of delivery gestational week≥28 weeks and newborn survival,260 cases were successful and 68 cases failed.Logistic regression was used to screen the influencing factors of pregnancy outcome after TVC.Results:Logistic regression analysis results showed that age,previous number of spontaneous abortion and/or preterm birth in the second trimester,assisted reproduction and postoperative complications were the risk factors of TVC pregnancy outcomes,and OR(95%CI)were 1.110(1.040-1.185),1.519(1.027-2.248),0.436(0.214-0.891)and 4.711(1.544-14.372),respectively.Conclusion:Age,the number of spontaneous abortion and/or preterm birth in the second trimester,assisted reproduction,and postoperative complications were influencing factors of TVC pregnancy outcomes.