肠球菌血流感染特征、危险因素及治疗方式

Characteristics, risk factors and treatment of Enterococcus bloodstream infection

肠球菌已成为院内获得性感染位居前列的重要病原菌,近年来,其高发病率、高致死率和由此产生的高医疗费用引起了医学界广泛的关注。本文分析了肠球菌血流感染的来源、相关危险因素以及肠球菌与高血压、糖尿病、癌症等多种疾病间相互关联等方面的特征,同时总结了多重耐药肠球菌在临床治疗用药等方面的进展,并关注了摆脱抗菌药物治疗依赖的新疗法-噬菌体治疗,以期为临床预防、精准治疗以及预后提供有价值的参考。

Enterococcus has become one of the most important pathogens in hospital-acquired infections.In recent years,its high morbidity,high mortality and high medical costs have attracted wide attention from the medical community.This article analyzes the source of Enterococcal bloodstream infections,related risk factors,and the characteristics of Enterococci in relation to hypertension,diabetes,cancer and other diseases.Meanwhile,it summarizes the progress of multi-drug resistant enterococci in clinical treatment,and focuses on a new therapy to get away from the dependence on antibiotics-phage therapy,in order to provide a valuable reference for clinical prevention,precise treatment and prognosis.