摘要
近20年来,近红外光谱技术因具有无创、实时等特点,被广泛用于人体监测。氧作为人体主要新陈代谢物质,在脑组织中消耗量最大,为防止患者治疗时出现脑组织氧降低而出现并发症,需要实时监测患者的脑组织血氧饱和度。目前临床使用的脑血氧无创检测设备大多采用双波长,在探测路径上其他物质会对测量结果产生误差,为此该研究基于近红外光谱无创监测脑血氧的基本原理,提出一种三波长探测光源的脑组织氧饱和度监测方法,并通过所搭建的系统进行初步验证,为后续的系统工程化奠定基础。
In the past 20 years,near infrared spectrum technology has been widely used in human body monitoring due to its non-invasive and real-time characteristics.Oxygen,as the main metabolic substance of the human body,is consumed the most in brain tissue.In order to prevent complications caused by a decrease in brain tissue oxygen during treatment,the patient's brain tissue blood oxygen saturation needs to be monitored in real time.Currently,most of the clinically used non-invasive cerebral blood oxygen detection equipments use dual wavelengths.Other substances on the detection path will cause errors in the measurement results.Therefore,this article proposes a three-wavelength method based on the basic principle of non-invasive monitoring of cerebral blood oxygen using near-infrared spectrum.The brain tissue oxygen saturation monitoring method of detecting light sources was initially verified through the built system,laying the foundation for subsequent system engineering.
作者
李泽熙
李翰林
尹琦
蔡世杰
叶继伦
张旭
于辉
勾大海
LI Zexi;LI Hanlin;YIN Qi;CAI Shijie;YE Jilun;ZHANG Xu;YU Hui;GOU Dahai(Guangdong BIOLIGHT Innovation Research Institute,Zhuhai,519080;School of Biomedical Engineering,Health Science Center,Shenzhen University,Shenzhen,518000;Key Laboratory of Biomedical Signal Detection and Ultrasound Imaging of Guangdong Province,Shenzhen,518000)
出处
《中国医疗器械杂志》
2024年第1期26-29,37,共5页
Chinese Journal of Medical Instrumentation
基金
珠海市人才项目(2120004000207)
深圳市科创委项目(JSGG20210713091811038)。
关键词
脑血氧
朗伯-比尔定律
近红外光谱
cerebral blood
Lambert-Beer law
near infrared spectrum