摘要
肾癌是泌尿系统常见的恶性肿瘤,起病隐匿,进展迅速。晚期肾癌预后差,主要依靠系统治疗。现行系统治疗方案主要为靶向治疗和免疫治疗。而新型靶向药物、靶向免疫联合新方案、HIF-2α抑制剂、益生菌联合治疗等为晚期肾癌系统治疗提供了更多可能。本文总结了近年来晚期肾癌系统治疗的现状及进展,以期为临床治疗提供借鉴。
Renal cell carcinoma is a common type of urinary cancer with insidious onset and rapid progression.Advanced renal cell carcinoma has poor prognosis and primarily depends on systemic therapy which mainly composed of targeted therapy and immunotherapy.Recently,new targeted drugs,immuno-targeted combination therapy,HIF-2αinhibitors,and probiotic combination therapy provide more possible options for the treatment.In this review,we gave an overview of the advances in systemic therapy of advanced renal cell carcinoma,aiming to help make clinical decisions.
作者
胡青岳
翟炜
郑军华
HU Qingyue;ZHAI Wei;ZHENG J unhua(Department of Urology,Renji Hospital,Shanghai Jiao Tong University School of Medicine,Shanghai 200127,China)
出处
《外科研究与新技术》
2023年第4期237-242,共6页
Surgical Research and New Technique
基金
国家自然科学基金项目(82173214)。
关键词
肾细胞癌
系统性治疗
靶向治疗
免疫治疗
Renal cell carcinoma
Systemic therapy
Targeted therapy
Immunotherapy
