中医外治法联合低分子肝素治疗脾肾两虚型复发性流产

External treatment of traditional Chinese medicine combined with low molecular weight heparin in the treatment of recurrent abortion with spleen-kidney deficiency

目的:探讨中医外治法联合低分子肝素治疗脾肾两虚型复发性流产的临床效果。方法:选择2021年1月至2022年12月收治的脾肾两虚型复发性流产患者90例,按照随机数字表法分为中医外治法组、低分子肝素组以及中医外治法联合低分子肝素组(联合治疗组),每组30例。治疗后,比较3组临床治疗有效率、血清激素水平和中医证候积分。结果:联合治疗组治疗总有效率76.67%高于低分子肝素组的43.33%及中医外治法组的50.00%,差异有统计学意义(P<0.05)。治疗后,3组血清激素水平均升高,联合治疗组高于低分子肝素组及中医外治法组(P<0.05);3组中医证候积分均降低,联合治疗组低于低分子肝素组及中医外治法组(P<0.05)。结论:脾肾两虚型复发性流产患者采用中医外治法联合低分子肝素治疗能提高血清激素水平,改善患者临床症状,提高临床治疗效果。

Objective:To investigate the clinical effect of external treatment of traditional Chinese medicine combined with low molecular weight heparin in the treatment of recurrent abortion with spleen-kidney deficiency.Methods:90 patients with recurrent miscarriage of spleen and kidney deficiency type admitted from January 2021 to December 2022 were randomly divided into the Chinese medicine external treatment group,low-molecular-weight heparin group,and Chinese medicine external treatment combined with low-molecular-weight heparin group(combined treatment group)using a random number table method,with 30 cases in each group.After treatment,the clinical efficacy,serum hormone indexes and TCM syndrome scores of the three groups were compared.Results:The total effective rate of 76.67%in the combined treatment group was higher than 43.33%in the low-molecular-weight heparin group and 50.00%in the traditional Chinese medicine external treatment group,with a statistically significant difference(P<0.05).Serum hormone indexes of the three groups were increased after treatment,and the combined treatment group was higher than the low-molecular-weight heparin group and the traditional Chinese medicine external treatment group(P<0.05).TCM syndrome scores in the three groups were all decreased,and the combined treatment group was lower than the low-molecular-weight heparin group and the TCM external treatment group(P<0.05).Conclusion:The external treatment of traditional Chinese medicine combined with low molecular weight heparin can improve the level of serum hormone indexes,the clinical symptoms,and clinical treatment effectiveness in the patients with recurrent abortion with spleen and kidney deficiency.