阿奇霉素不同给药方式联合胸腺五肽治疗支原体感染盆腔炎的效果

Effects of different administration methods of azithromycin combined with thymopentin on pelvic inflammatory disease caused by mycoplasma infection

目的:观察阿奇霉素不同给药方式联合胸腺五肽治疗支原体感染盆腔炎的效果。方法:将125例支原体感染盆腔炎患者随机分为两组,常规组62例,序贯组63例。常规组经口服阿奇霉素联合胸腺五肽注射治疗,序贯组经阿奇霉素序贯给药联合胸腺五肽注射治疗。比较两组炎症因子、子宫血流动力学、不良反应、细菌清除率和病情复发率。结果:治疗后,两组子宫血流动力学无统计学差异(P>0.05),序贯组的炎症因子、不良反应、病情复发率低于常规组,细菌清除率高于常规组,差异均具有统计学意义(P<0.05)。结论:阿奇霉素序贯给药联合胸腺肽治疗支原体感染盆腔炎效果显著。

Objective:To observe of the effects of different administration methods of azithromycin combined with thymopentin in the treatment of pelvic inflammatory disease caused by mycoplasma infection.Methods:125 patients with pelvic inflammatory disease caused by mycoplasma infection were randomly divided into two groups.There were 62 cases in the conventional group and 63 cases in the sequential group.The conventional group were treated with oral azithromycin combined with thymopentin injection,while the sequential group were treated with azithromycin sequential administration combined with thymopentin injection.Inflammatory factors,uterine hemodynamics,adverse reactions,bacterial clearance rate,and disease recurrence rate of two groups were compared.Results:After treatment,there was no statistically significant difference in uterine hemodynamics between the two groups(P>0.05).The inflammatory factors,adverse reactions,and relapse rate of the sequential group were lower than those of the conventional group,and the bacterial clearance rate of the sequential group was higher than that of the conventional group.The differences between the two groups were statistically significant(P<0.05).Conclusion:The sequential administration of azithromycin combined with thymosin has a significant effect in the treatment of pelvic inflammatory disease caused by mycoplasma infection.